Bacspa 10 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Baclofen |
| Company | Apex pharmaceuticals ltd |
Indications
- Spasticity resulting from multiple sclerosis
- Flexor spasms and concomitant pain, clonus and muscular rigidity
- Skeletal muscle spasm resulting from rheumatic disorders
- Spinal cord injuries and other spinal cord diseases
- Cerebrovascular accidents or neoplastic or degenerative brain disease
Pharmacology
- Inhibits monosynaptic and polysynaptic reflexes at spinal level
- Stimulates GABA receptors
- Inhibits release of glutamate and aspartate
- Antinociceptive effect
- Produces CNS depression
Dosage & Administration
- Adult & children over 10 years: 5 mg 3 times daily
- Preferably with or after food
- Gradually increased
- Max. 100 mg daily
- Children <10 years: Treatment is usually started with 2.5 mg (2.5 ml) given 4 times daily then raised according to requirement
- Daily maintenance dose: 12 month-2 years: 10-20 mg (10-20 ml), 2 years-6 years: 20-30 mg (20-30 ml), 6 years-10 years: 30-60 mg (30-60 ml)
Interaction
- Increased sedation with CNS acting agents, alcohol, synthetic opiates
- Increased risk of respiratory depression
- Likely increase in fall in blood pressure with antihypertensives
- Potentiation with tricyclic antidepressants
- Reported effects in patients with Parkinson’s disease receiving treatment with levodopa and carbidopa
- Concurrent use of MAO inhibitors
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Transient drowsiness
- Daytime sedation
- Dizziness
- Weakness
- Fatigue
- Various Central Nervous System effects
- Cardiovascular effects
- Gastrointestinal effects
- Genitourinary effects
- Other adverse reactions
Pregnancy & Lactation
- Pregnancy category B3
- Safe use during pregnancy not established
- Excretion in breast milk
Precautions & Warnings
- Lower doses for impaired renal function
- Cautious treatment for patients with psychotic disorders
- Epilepsy patients and muscle spasticity
- Caution for patients with peptic ulcers, cerebrovascular diseases, or hepatic, renal or respiratory failure
- Monitoring of respiratory and cardiovascular function
- Possible improvement of neurogenic disturbances affecting bladder emptying
- Poor tolerance in stroke patients
Overdose Effects
- Gastric lavage in case of severe overdose
Therapeutic Class
- Centrally acting Skeletal Muscle Relaxants
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children