Onsat OSF 8 mg (Oral Soluble Film)

Unit Price: ৳ 18.00 (1 x 10: ৳ 180.00)

Medicine Details

Indications

  • Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
  • Prevention and treatment of post-operative nausea and vomiting
  • Prevention of radiotherapy-induced nausea and vomiting

Dosage

  • 8 mg tablet/orodispersible tablet
  • 4 mg orodispersible tablet
  • Injection
  • Highly emetogenic cancer chemotherapy
  • Moderate emetogenic cancer chemotherapy
  • Pediatric (4-11 years)
  • Oral solution
  • Postoperative Nausea and Vomiting
  • Total body irradiation
  • Single high-dose fraction radiotherapy to the abdomen
  • Daily fractionated radiotherapy to the abdomen
  • Adult oral dose
  • Pediatric patients 12 years of age and older
  • Child of 12 years or over
  • Pediatrics (>40 kg)
  • Pediatrics (40 kg)
  • Pediatrics (6 months to 18 years)
  • Adults
  • Adults/Geriatric/Child of 12 years or over

Administration

  • Tear the pouch carefully along with the edge tear mark
  • Put the Ondansetron film on top of your tongue
  • It will dissolve within 20 seconds
  • Do not chew or swallow the film whole
  • Swallow after the Onsaf oral soluble film dissolves
  • Wash your hands after taking Onsaf oral soluble film

Interaction

  • Does not induce or inhibit the cytochrome P-450 drug-metabolizing enzyme system of the liver
  • Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes

Contraindications

  • Hypersensitivity to the drug or any of its components
  • Concomitant use of apomorphine

Side Effects

  • Headache
  • Constipation
  • Diarrhea
  • Rash
  • Sensation of flushing or warmth
  • Hiccups
  • Liver enzyme abnormalities
  • Anaphylaxis
  • Brochospasm
  • Tachycardia
  • Angina (chest pain)
  • Hypokalemia
  • Shortness of breath
  • Flushing or warmth
  • Liver enzyme abnormalities
  • Extrapyramidal reactions
  • Oculogyric crisis
  • PONV
  • Bronchospasm
  • Anaphylaxis

Pregnancy & Lactation

  • No evidence of impaired fertility or harm to the fetus
  • Excreted in the breast milk of rats
  • Caution when administered to nursing women

Precautions & Warnings

  • Hypersensitivity reactions
  • Not a drug that stimulates gastric or intestinal peristalsis
  • Should not be used instead of nasogastric suction
  • May mask a progressive ileus and/or gastric distension

Use in Special Populations

  • Dosage Adjustment for Patients With Impaired Renal Function
  • Dosage Adjustment for Patients With Impaired Hepatic Function
  • Little information about dosage in pediatric patients 4 years of age or younger
  • Dosage adjustment not needed in patients over the age of 65

Therapeutic Class

Anti-emetic drugs

Storage Conditions

Store at temperature not exceeding 30ºC in a dry place. Protect from light and moisture

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