VomitOF 4 mg/5 ml (Oral Solution)
50 ml bottle: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Chemist laboratories ltd |
| Also available as |
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Dosage
- 8 mg tablet/orodispersible tablet
- 4 mg orodispersible tablet
- Injection
- Pediatric dosage
- Dosage for different types of chemotherapy and radiotherapy
Mode of Action
- Selective blocking agent of the serotonin 5-HT3 receptor type
- Mechanism of action in chemotherapy and radiotherapy-induced nausea and vomiting
Pharmacology
- Potent, highly selective 5HT3 receptor-antagonist
- Precise mode of action not fully known
- Interactions with chemotherapeutic agents and radiotherapy
Administration
- Instructions for oral soluble film administration
- Steps for using the oral soluble film
Interaction
- Metabolism by hepatic cytochrome P-450 drug-metabolizing enzymes
- Effects of inducers or inhibitors of cytochrome P-450 enzymes on clearance and half-life
Contraindications
- Hypersensitivity to the drug or any of its components
- Concomitant use of apomorphine
Side Effects
- Frequently reported adverse events
- Rare cases of severe adverse reactions
- Occurrence of adverse events in different patient groups
Pregnancy & Lactation
- Carcinogenic and mutagenic effects in animal studies
- Excretion in breast milk
- Caution in nursing women
Precautions & Warnings
- Reported hypersensitivity reactions
- Use in patients with abdominal surgery or chemotherapy-induced nausea and vomiting
- Avoid use instead of nasogastric suction
Use in Special Populations
- Dosage adjustment for patients with impaired renal function
- Dosage for patients with impaired hepatic function
- Limited information on dosage for young pediatric patients
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Temperature and environmental storage requirements