Emiston 4 mg/5 ml (Oral Solution)

50 ml bottle: ৳ 50.00

Medicine Details

Indications

  • Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
  • Prevention and treatment of post-operative nausea and vomiting
  • Prevention of radiotherapy-induced nausea and vomiting

Dosage

  • 8 mg tablet/orodispersible tablet for chemotherapy-induced nausea and vomiting
  • 4 mg orodispersible tablet for radiotherapy-induced nausea and vomiting
  • 3 0.15 mg/kg doses for pediatric patients
  • Highly emetogenic cancer chemotherapy dosage for adults and pediatric patients
  • Moderate emetogenic cancer chemotherapy dosage for adults and pediatric patients
  • Pediatric dosage for ages 4-11 years
  • Radiotherapy-induced nausea and vomiting dosage for adults and pediatric patients
  • Postoperative nausea and vomiting dosage for adults and pediatric patients
  • Adult oral dose for prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy
  • Adult and pediatric patients dosage for moderately emetogenic cancer chemotherapy
  • Oral soluble film dosage for prevention of nausea and vomiting associated with radiotherapy
  • Adult dose for postoperative nausea and vomiting

Administration

  • Tear the pouch carefully along with the edge tear mark
  • Put the oral soluble film on top of your tongue. It will dissolve within 20 seconds
  • Do not chew or swallow the film whole
  • Swallow after the film dissolves
  • Wash your hands after taking the oral soluble film

Interactions

  • Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes

Contraindications

  • Hypersensitivity to the drug or any of its components
  • Concomitant use of apomorphine

Side Effects

  • Frequently reported adverse events including headache, constipation, and diarrhea
  • Rare cases of anaphylaxis, brochospasm, tachycardia, and angina
  • No evidence of extrapyramidal reactions
  • Rates of events were not significantly different in the Emiston and placebo groups

Pregnancy & Lactation

  • Carcinogenic effects were not seen in 2-year studies in rats and mice
  • No evidence of impaired fertility or harm to the fetus
  • No adequate and well-controlled studies in pregnant women
  • Excreted in the breast milk of rats

Precautions & Warnings

  • Hypersensitivity reactions reported in patients with hypersensitivity to other selective 5-HT3 receptor antagonists
  • Not a drug that stimulates gastric or intestinal peristalsis
  • Should not be used instead of nasogastric suction
  • Use in patients following abdominal surgery or with chemotherapy-induced nausea and vomiting may mask a progressive ileus and/or gastric distension

Use in Special Populations

  • Dosage adjustment for patients with impaired renal function
  • Dosage adjustment for patients with impaired hepatic function
  • Little information available about dosage in pediatric patients 4 years of age or younger

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Store at temperature not exceeding 30°C in a dry place
  • Protect from light and moisture

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