Nauset 4 mg/5 ml (Oral Solution)
50 ml bottle: ৳ 45.13
Medicine Details
Category | Details |
---|---|
Generic | Ondansetron |
Company | Navana pharmaceuticals ltd |
Also available as |
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Dosage
- 8 mg tablet/orodispersible tablet
- 4 mg orodispersible tablet
- Injection
- 30 ml (24 mg) Ondansetron Oral Solution
- 10 ml (8 mg) Ondansetron Oral Solution
- 5 ml (4 mg) Ondansetron Oral Solution
- 20 ml (16 mg) Ondansetron Oral Solution
- Oral soluble film
Pharmacology
Ondansetron is a potent, highly selective 5HT3 receptor-antagonist. Its precise mode of action in the control of nausea and vomiting is not known.
Administration
- Tear the pouch carefully along with the edge tear mark
- Put the Ondansetron film on top of your tongue. It will dissolve within 20 seconds
- Do not chew or swallow the film whole
- Swallow after the Onsaf oral soluble film dissolves
- Wash your hands after taking Onsaf oral soluble film
Interaction
Nauset does not itself appear to induce or inhibit the cytochrome P-450 drug-metabolizing enzyme system of the liver.
Contraindications
Contraindicated in patients known to have hypersensitivity to the drug or any of its components. Concomitant use of apomorphine.
Side Effects
- Headache
- Constipation
- Diarrhea
- Rash
- Sensation of flushing or warmth
- Hiccups
- Liver enzyme abnormalities
- Anaphylaxis
- Bronchospasm
- Tachycardia
- Angina (chest pain)
- Hypokalemia
- Shortness of breath
Pregnancy & Lactation
- Carcinogenic effects were not seen in 2-year studies in rats and mice with oral Ondansetron doses up to 10 and 30 mg/kg per day, respectively
- Ondansetron was not mutagenic in standard tests for mutagenicity
- Reproduction studies have been performed in pregnant rats and rabbits at daily oral doses up to 15 and 30 mg/kg per day, respectively, and have revealed no evidence of impaired fertility or harm to the fetus due to Ondansetron
Precautions & Warnings
- Hypersensitivity reactions have been reported in patients who have exhibited hypersensitivity to other selective 5-HT3 receptor antagonists
- Nauset is not a drug that stimulates gastric or intestinal peristalsis
- The use of Nauset in patients following abdominal surgery or in patients with chemotherapy-induced nausea and vomiting may mask a progressive ileus and/or gastric distension
Therapeutic Class
Anti-emetic drugs
Storage Conditions
Store at temperature not exceeding 30°C in a dry place. Protect from light and moisture