Nauset 8 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Title
- Nauset Oral Soluble Film
Categories
- Anti-emetic drugs
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Dosage
- Oral soluble film designed to be applied on top of the tongue and dissolve within 20 seconds
- Dosage varies for adults, pediatric patients, and different types of nausea and vomiting
Mode of Action
- Potent, highly selective 5HT3 receptor-antagonist
- Precise mode of action in the control of nausea and vomiting is not fully known
- Blocks initiation of vomiting reflex by activating vagal afferents via 5HT3 receptors
Administration
- Step-by-step guide for administration of oral soluble film
- No need for water to aid dissolution or swallowing
Interaction
- Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes
- Inducers or inhibitors of these enzymes may affect its clearance and half-life
Contraindications
- Contraindicated in patients known to have hypersensitivity to the drug or any of its components
- Concomitant use of apomorphine
Side Effects
- Frequently reported adverse events include headache, constipation, and diarrhea
- Rare cases of anaphylaxis, bronchospasm, tachycardia, angina, hypokalemia, and shortness of breath
Pregnancy & Lactation
- No evidence of impaired fertility or harm to the fetus in animal studies
- Cautious use in pregnant and nursing women due to excretion in breast milk
Precautions & Warnings
- Hypersensitivity reactions reported in patients with hypersensitivity to other selective 5-HT3 receptor antagonists
- Not a drug that stimulates gastric or intestinal peristalsis
- Caution needed in patients following abdominal surgery or with chemotherapy-induced nausea and vomiting
Use in Special Populations
- Dosage adjustment not needed for patients with impaired renal function
- Different dosage recommendation for patients with severe hepatic impairment
- Limited information about dosage in pediatric patients 4 years of age or younger
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Store at temperature not exceeding 30°C in a dry place
- Protect from light and moisture