Dantron 8 mg (Tablet)
Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | One pharma ltd |
| Also available as |
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Dosage
- Adults, Pediatric patients (6 months to 18 years)
- 8 mg tablet/orodispersible tablet
- 4 mg orodispersible tablet
- Injection
- Pediatrics (>40 kg)
- Pediatrics (40 kg)
- Highly emetogenic cancer chemotherapy
- Moderate emetogenic cancer chemotherapy
- Pediatric (4-11 years)
- Radiotherapy induced Nausea and Vomiting (Adults/Geriatric/Child of 12 years or over)
- Total body irradiation
- Single high-dose fraction radiotherapy to the abdomen
- Daily fractionated radiotherapy to the abdomen
- Postoperative Nausea and Vomiting (Adults/Geriatric/Child of 12 years or over)
- Oral solution
- Oral Soluble Film
- Adults and pediatric patients 12 years of age and older
- Pediatric patients 4 through 11 years of age
- Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy
- Prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy
- Prevention of nausea and vomiting associated with radiotherapy
- Postoperative nausea and vomiting
Pharmacology
- Selective blocking agent of the serotonin 5-HT3 receptor type
- Mode of action in the management of the nausea and vomiting induced by cytotoxic chemotherapy and radiotherapy
Administration
- Tear the pouch carefully along with the edge tear mark
- Put the Ondansetron film on top of your tongue
- Do not chew or swallow the film whole
- Swallow after the Onsaf oral soluble film dissolves
- Wash your hands after taking Onsaf oral soluble film
Interaction
- Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes
- Inducers or inhibitors of these enzymes may change the clearance and half-life
Contraindications
- Hypersensitivity to the drug or any of its components
- Concomitant use of apomorphine
Side Effects
- Headache
- Constipation
- Diarrhea
- Rash
- Sensation of flushing or warmth
- Hiccups
- Liver enzyme abnormalities
- Anaphylaxis
- Bronchospasm
- Tachycardia
- Angina (chest pain)
- Hypokalemia
- Shortness of breath
- Extrapyramidal reactions
- Oculogyric crisis
- Postoperative Nausea and Vomiting (PONV)
Pregnancy & Lactation
- Not mutagenic in standard tests for mutagenicity
- No evidence of impaired fertility or harm to the fetus
- Excreted in the breast milk of rats
- Caution when administered to a nursing women
Precautions & Warnings
- Hypersensitivity reactions
- Not a drug that stimulates gastric or intestinal peristalsis
- Should not be used instead of nasogastric suction
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Temperature not exceeding 30°C in a dry place
- Protect from light and moisture