Dantron 4 mg/5 ml (Oral Solution)
50 ml bottle: ৳ 45.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | One pharma ltd |
| Also available as |
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Formulation Type
Oral Soluble Film
Active Ingredient
Dantron base
Molecular Weight
293.3
Dosage Instructions
- Adults, Pediatric patients (6 months to 18 years): Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose
- Adults: Initial Dose: 8 mg orally 1 to 2 hours before radiotherapy. Post Radiotherapy: 8 mg orally every 8 hours for up to 5 days after a course of treatment
- Adults: 16 mg given as two 8 mg tablets
- Pediatrics (>40 kg): Injection: 4 mg
Administration
- Tear the pouch carefully along with the edge tear mark
- Put the Ondansetron film on top of your tongue. It will dissolve within 20 seconds
- Do not chew or swallow the film whole
- Swallow after the Onsaf oral soluble film dissolves. You may swallow the dissolved film with or without liquid
- Wash your hands after taking Onsaf oral soluble film
Mode of Action
Selective blocking agent of the serotonin 5-HT3 receptor type
Interaction
Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes
Contraindications
Hypersensitivity to the drug or any of its components
Side Effects
- Headache
- Constipation
- Diarrhea
- Rash
- Sensation of flushing or warmth
- Hiccups
- Liver enzyme abnormalities
- Anaphylaxis
- Brochospasm
- Tachycardia
- Angina (chest pain)
- Hypokalemia
Pregnancy & Lactation
No evidence of impaired fertility or harm to the fetus due to Ondansetron
Precautions & Warnings
- Hypersensitivity reactions reported
- Not a drug that stimulates gastric or intestinal peristalsis
- Should not be used instead of nasogastric suction
- May mask a progressive ileus and/or gastric distension
Therapeutic Class
Anti-emetic drugs
Storage Conditions
Store at temperature not exceeding 30ºC in a dry place. Protect from light and moisture