Novatron 8 mg/4 ml (IM/IV Injection)
4 ml ampoule: ৳ 30.00 (1 x 5: ৳ 150.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Radiant pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of nausea and vomiting associated with emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Formulation
- Oral soluble film
Active Ingredient
- Ondansetron
Molecular Weight
- 293.3
Mode of Action
- Selective blocking agent of serotonin 5-HT3 receptor type
- Antagonism of 5HT3 receptors in peripheral and central nervous system
Dosage
- 8 mg orodispersible tablet
- 4 mg orodispersible tablet
- Injection dosage
- Dosage for different age groups
Administration
- Dissolves within 20 seconds on top of the tongue
- Does not require water for swallowing
Interaction
- Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes
- May interact with inducers or inhibitors of these enzymes
Contraindications
- Hypersensitivity to the drug or its components
- Concomitant use of apomorphine
Side Effects
- Headache
- Constipation
- Diarrhea
- Rash
- Sensation of flushing or warmth
- Hiccups
- Abnormal liver enzymes
- Rare severe adverse effects
Pregnancy & Lactation
- No evidence of harm to fetus from animal studies
- Exercise caution in nursing women
Precautions & Warnings
- Hypersensitivity reactions reported
- Does not stimulate gastric or intestinal peristalsis
- Should not be used in place of nasogastric suction
Use in Special Populations
- Dosage adjustment for impaired renal function
- Dosage adjustment for impaired hepatic function
- Limited information on use in pediatric patients 4 years and younger
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Store at temperature not exceeding 30°C
- Protect from light and moisture