Pukenil 8 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Team pharmaceuticals ltd |
| Also available as |
Title and Categories
- Pukenil Oral Soluble Film
- Medicine
- Anti-emetic drugs
Dimensions and Size Options
Color Options
Functions
- Prevention of nausea and vomiting associated with emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
- Selective blocking agent of the serotonin 5-HT3 receptor type
Materials
- Ondansetron
- Pukenil base
- C18H19N3O
- Racemic form of Ondansetron
Technical Specifications
- Molecular weight of 293.3
- Indicated for adults, pediatric patients, geriatric patients, and children over 12 years
Design Elements
- Orally dissolving film designed to be applied on top of the tongue
- Does not require water to aid dissolution or swallowing
Usability Features
- Dissolves within 20 seconds on top of the tongue
- Can be swallowed with saliva without the need for water
Dosage
- 8 mg and 4 mg oral soluble film doses for adults and pediatric patients
- 16 mg per dose maximum
Administration
- Oral soluble film administration steps
Interaction
- Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes
- No dosage adjustment recommended for patients on drugs inducing or inhibiting these enzymes
Contraindications
- Hypersensitivity to the drug or any of its components
- Concomitant use of apomorphine
Side Effects
- Frequently reported adverse events including headache, constipation, and diarrhea
- Rash reported in chemotherapy-induced nausea and vomiting
- Rare cases of anaphylaxis, brochospasm, tachycardia, angina, hypokalemia, and shortness of breath
Pregnancy & Lactation
- No evidence of impaired fertility or harm to the fetus due to Ondansetron in animal studies
- Caution advised when administered to nursing women
Precautions & Warnings
- Hypersensitivity reactions reported in patients who have exhibited hypersensitivity to other selective 5-HT3 receptor antagonists
- Not a drug that stimulates gastric or intestinal peristalsis
- Should not be used instead of nasogastric suction
Use in Special Populations
- Same dosage recommendation for patients with impaired renal function
- Recommended single maximal daily dose of 8 mg for patients with severe hepatic impairment
- Little information available about dosage in pediatric patients 4 years of age or younger
- No dosage adjustment needed in patients over the age of 65
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Store at a temperature not exceeding 30°C in a dry place
- Protect from light and moisture