Nitoxin 100 mg/5 ml (Powder for Suspension)

30 ml bottle: ৳ 36.00

Medicine Details

Category Details
Generic Nitazoxanide
Company Aristopharma ltd
Also available as
Nitoxin 500 mg tablet

Indications

  • Treatment of diarrhea caused by Cryptosporidium parvum
  • Treatment of diarrhea caused by Giardia lamblia
  • Treatment of diarrhea caused by Entamoeba histolytica

Pharmacology

  • Synthetic antiprotozoal agent for oral administration
  • Interference with the Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme-dependent electron transfer reaction
  • Inhibition of growth of sporozoites and oocyst of Cryptosporidium parvum
  • Inhibition of growth of trophozoites of Giardia lamblia

Dosage & Administration

  • Dosage varies by age group
  • Recommended to be administered with food

Interaction

  • Highly bound to plasma protein
  • Caution required when administering concurrently with other highly plasma protein-bound drugs with narrow therapeutic index

Contraindications

  • Contraindicated in patients with known hypersensitivity to Nitazoxanide or any components of the preparation

Side Effects

  • Most frequent side effects include abdominal pain, vomiting, and headache
  • Rare side effects include nausea, anorexia, flatulence, increased appetite, enlarged salivary glands, increased creatinine & SGPT level, pruritus, rhinitis, sweating, dizziness, discolored urine

Pregnancy & Lactation

  • US FDA pregnancy category is B
  • Caution required during pregnancy and lactation

Precautions & Warnings

  • Caution required for patients with hepatic & biliary disease
  • Caution required for patients with renal disease

Therapeutic Class

  • Anti-diarrhoeal
  • Antiprotozoal

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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