Nixar 500 mg (Tablet)

Unit Price: ৳ 10.03 (2 x 10: ৳ 200.60)
Strip Price: ৳ 100.30

Medicine Details

Category Details
Generic Nitazoxanide
Company Sharif pharmaceuticals ltd
Also available as
Nixar 100 mg suspension

Indications

  • Treatment of diarrhea caused by Cryptosporidium parvum
  • Treatment of diarrhea caused by Giardia lamblia
  • Treatment of diarrhea caused by Entamoeba histolytica

Pharmacology

  • Nitazoxanide is a synthetic antiprotozoal agent
  • Administration: Oral
  • Mechanism of Action: Interference with Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme-dependant electron transfer reaction
  • Activity: Inhibiting the growth of sporozoites and oocyst of Cryptosporidium parvum
  • Activity: Inhibiting the growth of trophozoites of Giardia lamblia

Dosage & Administration

  • Age 1-3 years: 1 tea-spoonfull or 5 ml suspension every 12 hours for 3 days
  • Age 4-11 years: 2 tea-spoonfulls or 10 ml suspension every 12 hours for 3 days
  • Age 12 years or above: 5 tea-spoonfulls (25 ml) suspension or 1 tablet every 12 hours for 3 days
  • Administration with food: Recommended

Interaction

  • Caution needed when administering Nixar concurrently with other highly plasma protein-bound drugs with narrow therapeutic index

Contraindications

  • Known hypersensitivity to Nitazoxanide or any components of the preparation

Side Effects

  • Most frequent: Abdominal pain, vomiting, headache (mild and transient in nature)
  • Rare: Nausea, anorexia, flatulence, increased appetite, enlarged salivary glands, increased creatinine & SGPT level, pruritus, rhinitis, sweating, dizziness, discolored urine

Pregnancy & Lactation

  • US FDA pregnancy category: B
  • Use during pregnancy if clearly needed
  • Excreted in human milk: Yes
  • Caution during lactation: Recommended

Precautions & Warnings

  • Caution in patients with hepatic & biliary disease
  • Caution in patients with renal disease

Therapeutic Class

  • Anti-diarrhoeal
  • Antiprotozoal

Storage Conditions

  • Dry place
  • Away from light and heat
  • Keep out of the reach of children

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