Palosis 0.5 mg (Capsule)

Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Palonosetron
Company Eskayef pharmaceuticals ltd
Also available as
Palosis 05 mg tablet Palosis 0075 mg injection Palosis 025 mg injection

Title and Description

  • Palonosetron injection
  • Anti-emetic drug for nausea and vomiting

Categories

  • Pharmaceuticals
  • Health and Wellness

Color Options

  • Clear liquid

Dosage Form

  • Tablet
  • Injection

Mode of Action

  • 5-HT3 receptor antagonist
  • Blocks serotonin actions

Pharmacology

  • Linear dose-proportional pharmacokinetics
  • Metabolized via kidney and liver CYP2D6, CYP3A4, and CYP1A2 isoenzymes
  • Longer half-life (40 hours)

Dosage and Administration

  • Adult tablet dosage: 0.5 mg daily
  • Adult IV dosage: 0.075 mg over 10 seconds
  • Usual dosage for children: A single IV dose at 20 mcg/kg body weight

Interaction

  • Safely administered with corticosteroids, analgesics, antiemetics/antinauseants
  • No significant pharmacokinetic interactions with metoclopramide

Contraindications

  • Hypersensitivity to the drug or its components

Side Effects

  • Headaches
  • Constipation

Pregnancy & Lactation

  • Pregnancy category 'B'
  • Unknown excretion in breast milk

Use in Special Populations

  • No dosage adjustment in elderly patients
  • Special dosage for children aged 1 month to 10 years
  • No dosage adjustment in patients with renal and hepatic dysfunction

Overdose Effects

  • No known antidote
  • Managed with supportive care

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Store in a cool & dry place, protected from light

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