Palanomed 0.5 mg (Tablet)

Unit Price: ৳ 20.00

Medicine Details

Category Details
Generic Palonosetron
Company Medrx life science ltd

Indications

  • Acute and delayed nausea and vomiting
  • Uncontrolled nausea and vomiting
  • Chemotherapy-induced nausea and vomiting (CINV)
  • Radiotherapy-induced nausea and vomiting (RINV)
  • Post-operative & Post-discharge nausea and vomiting (PONV & PDNV)

Pharmacology

  • 5-HT3 receptor antagonist
  • Strong binding affinity for 5-HT3 receptor
  • Little or no affinity for other receptors
  • Influences postoperative nausea and vomiting
  • Selective participation in emetic response

Dosage & Administration

  • Adult tablet dosage: 0.5 mg daily
  • Adult IV dosage: A single IV dose of 0.075 mg over 10 seconds
  • Dosage for chemotherapy-induced nausea and vomiting
  • Dosage for radiotherapy-induced nausea and vomiting
  • Dosage for post-operative nausea and vomiting
  • Children dosage: single IV dose at 20 mcg/kg body weight with maximum 1.5 mg

Interaction

  • Safely administered with corticosteroids, analgesics, antiemetics/antinauseants
  • No inhibitory effects on antitumor activity of certain drugs
  • No significant pharmacokinetic interactions with metoclopramide
  • Low potential for clinically significant drug interactions

Contraindications

  • Hypersensitivity to the drug or any of its components

Side Effects

  • Headaches
  • Constipation

Pregnancy & Lactation

  • Pregnancy category 'B'
  • Unknown excretion in breast milk

Use in Special Populations

  • No dosage adjustment recommended in elderly patients
  • Dosage information for children (1 month to 10 years)
  • No dosage adjustment recommended in patients with renal and hepatic dysfunction

Overdose Effects

  • No known antidote
  • Managed with supportive care

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Store in a cool & dry place
  • Protected from light

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