Palostar 0.075 mg/1.5 ml (IV Injection)

1.5 ml ampoule: ৳ 75.00 (1 x 5: ৳ 375.00)

Medicine Details

Category Details
Generic Palonosetron
Company Orion pharma ltd
Also available as

Indications

  • Acute and delayed nausea and vomiting
  • Uncontrolled nausea and vomiting
  • Chemotherapy-induced nausea and vomiting (CINV)
  • Radiotherapy-induced nausea and vomiting (RINV)
  • Post-operative & Post-discharge nausea and vomiting (PONV & PDNV)

Pharmacology

  • 5-HT3 receptor antagonist
  • Chemotherapeutic agents mechanism
  • Activation of 5-HT3 receptors
  • Pharmacokinetics
  • Metabolism
  • Excretion
  • Binding affinity

Dosage & Administration

  • Adult tablet dosage
  • Adult IV dosage
  • Usual dosage
  • Chemotherapy-induced nausea and vomiting dosage
  • Radiotherapy-induced nausea and vomiting dosage
  • Post-operative nausea and vomiting dosage
  • Children dosage

Interaction

  • Safety with other medications
  • Inhibition of CYP enzymes
  • Absence of significant drug interactions

Contraindications

  • Hypersensitivity to the drug or its components

Side Effects

  • Headaches
  • Constipation

Pregnancy & Lactation

  • Pregnancy category 'B'
  • Excretion in breast milk

Use in Special Populations

  • Elderly patients dosage adjustment
  • Use in Children
  • Use in patients with impaired renal and hepatic function

Overdose Effects

  • No known antidote
  • Supportive care for management

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Cool & dry place
  • Protected from light

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