Palostar 0.5 mg (Tablet)
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Palonosetron |
| Company | Orion pharma ltd |
| Also available as |
Indications
- Acute and delayed nausea and vomiting
- Uncontrolled nausea and vomiting
- Chemotherapy-induced nausea and vomiting (CINV)
- Radiotherapy-induced nausea and vomiting (RINV)
- Post-operative & Post-discharge nausea and vomiting (PONV & PDNV)
Pharmacology
- 5-HT3 receptor antagonist
- Binding affinity for 5-HT3 receptor
- Inhibition of serotonin actions
- Central and peripheral emetic response
- Metabolism and excretion kinetics
Dosage & Administration
- Adult tablet dosage: 0.5 mg daily
- Adult IV dosage: 0.075 mg over 10 seconds
- Usage before chemotherapy and radiotherapy
- Pediatric dosage: 20 mcg/kg body weight
Interaction
- Safe administration with corticosteroids and analgesics
- No inhibition of antitumor activity
- No significant pharmacokinetic interactions
- Low potential for drug interactions
Contraindications
- Hypersensitivity to the drug or its components
Side Effects
- Headaches
- Constipation
Pregnancy & Lactation
- Pregnancy category 'B'
- Unknown excretion in breast milk
Use in Special Populations
- No dosage adjustment for elderly patients
- Dosage adjustment for children and patients with impaired renal and hepatic function
Overdose Effects
- No known antidote
- Supportive care for management
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Store in a cool & dry place
- Protected from light