Pantotop 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 6.00 (7 x 10: ৳ 420.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Pantoprazole sodium
Company Benham pharmaceuticals ltd
Also available as
Pantotop 40 mg tablet

Indications

  • Peptic ulcer diseases
  • Gastroesophageal reflux diseases
  • Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Eradication of Helicobacter pylori (in combination with antibiotics)
  • Zollinger-Ellison Syndrome

Pharmacology

Pantoprazole is a proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell.

Dosage & Administration

  • Benign gastric ulcer: 40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed
  • Gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed; maintenance dose is 20 mg daily, which may be increased to 40 mg daily
  • Duodenal ulcer: 40 mg daily in the morning for 2 weeks, continued for further 2 weeks if not fully healed
  • Duodenal ulcer associated with Helicobacter pylori: Pantoprazole is recommended at a dose of 40 mg twice daily in association with antimicrobial agents
  • Prophylaxis of NSAID-associated gastric or duodenal ulcer: 20 mg daily for those require long-term NSAID treatment
  • Zollinger-Ellison Syndrome: Initially 80 mg once daily adjusted according to response

Interaction

No significant drug interactions have been observed in clinical studies.

Contraindications

Pantoprazole is contraindicated in patients with known hypersensitivity to any of the components of the formulation.

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Rash
  • Insomnia
  • Hyperglycemia

Pregnancy & Lactation

US FDA Pregnancy Category of Pantoprazole is B. There are, however, no adequate and well-controlled studies in pregnant woman.

Precautions & Warnings

Patients should be cautioned that Pantotop tablet should not be split, chewed or crushed. Long-term therapy of Pantotop may lead to malabsorption of cyanocobalamin (Vitamin B12) or may increase the risk of osteoporosis related disorders.

Overdose Effects

There are no known symptoms of overdosage in humans. Since Pantotop is highly protein bound, it is not readily dialyzable.

Therapeutic Class

Proton Pump Inhibitor

Reconstitution

  • Direction for use of IV injection
  • Direction for use of IV infusion

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children.

Chemical Structure

  • Molecular Formula: C16H15F2N3O4S
  • Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg

Common Questions about Pantotop 20 mg Tablet

  • What is Pantotop 20 mg Tablet?
  • How long do I need to use Pantotop 20 mg Tablet before I see improvement in my condition?
  • At what frequency do I need to use Pantotop 20 mg Tablet?
  • Should I use Pantotop 20 mg Tablet empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Pantotop 20 mg Tablet?
  • What are the effects of Pantotop 20 mg Tablet on older adults?
  • How long does it take for Pantotop 20 mg Tablet to work?
  • Is Pantotop 20 mg Tablet safe?
  • Does Pantotop 20 mg Tablet cause weight gain?
  • What are the side effects of Pantotop 20 mg Tablet?
  • Can I take Pantotop 20 mg Tablet if I am pregnant or breastfeeding?
  • What should I do if I miss a dose of Pantotop 20 mg Tablet?

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