Pantobio 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 4.75 (5 x 14: ৳ 332.50)
Strip Price: ৳ 66.50

Medicine Details

Category Details
Generic Pantoprazole sodium
Company Biogen pharmaceuticals ltd

Title

  • Pantobio 20 mg Tablet

Categories

  • Medicine
  • Health
  • Pharmaceutical

Description

  • Pantobio is a proton pump inhibitor indicated for peptic ulcer diseases, gastroesophageal reflux diseases, ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs), eradication of Helicobacter pylori, and Zollinger-Ellison Syndrome. It suppresses the final step in gastric acid production.

Dosage and administration

  • Oral dosage for benign gastric ulcer, gastro-esophageal reflux disease (GERD), duodenal ulcer, duodenal ulcer associated with Helicobacter pylori, prophylaxis of NSAID-associated gastric or duodenal ulcer, and Zollinger-Ellison Syndrome. Intravenous (IV) injection dosage for duodenal ulcer, gastric ulcer, gastroesophageal reflux disease, prevention of rebleeding in peptic ulcer, prophylaxis of acid aspiration, and long-term management of Zollinger-Ellison Syndrome and other pathological hypersecretory conditions.

Therapeutic class

  • Proton Pump Inhibitor

Pregnancy and lactation

  • Pantoprazole is categorized as US FDA Pregnancy Category B. Caution is advised as there are no adequate and well-controlled studies in pregnant women. It is excreted in human milk so a decision should be made whether to discontinue nursing.

Side effects

  • Common side effects include headache, diarrhea, abdominal pain, flatulence, rash, insomnia, and hyperglycemia. Generally well tolerated in both short-term and long-term treatment.

Precautions and warnings

  • Patients should be cautioned against splitting, chewing, or crushing the tablet. Long-term use may lead to malabsorption of cyanocobalamin (Vitamin B12) or increase the risk of osteoporosis related disorders.

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the components of the formulation.

Interaction

  • No significant drug interactions observed in clinical studies.

Overdose effects

  • No known symptoms of overdosage in humans. Since it is highly protein bound, it is not readily dialyzable. Apart from symptomatic and supportive management, no specific therapy is recommended.

Reconstitution

  • For intravenous administration only, reconstitution and administration instructions for IV injection and IV infusion provided.

Storage conditions

  • Keep in a dry place, away from light and heat. Keep out of the reach of children.

Chemical structure

  • Molecular Formula: C16H15F2N3O4S

Indications

  • Suppression of acid secretion has therapeutic benefit for peptic ulcer diseases, gastroesophageal reflux diseases, ulcer induced by NSAIDs, eradication of Helicobacter pylori, and Zollinger-Ellison Syndrome.

Commonly asked questions

  • Common questions and answers about Pantobio 20 mg Tablet including usage, frequency, storage and disposal, effects on older adults, effectiveness duration, safety, weight gain, side effects, pregnancy and breastfeeding, and missed dose.

Pharmacology

  • Pantoprazole is a proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell, leading to inhibition of both basal and stimulated gastric acid secretion.

Prevention

  • Prophylaxis of NSAID-associated gastric or duodenal ulcer

Warning

  • Long-term therapy may lead to malabsorption of cyanocobalamin (Vitamin B12) or increase the risk of osteoporosis related disorders.

Overdose management

  • No specific therapy is recommended for overdosage, and it is not readily dialyzable due to high protein binding.

Administration methods

  • Oral
  • Intravenous (IV) Injection
  • IV Infusion

Potential side effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Rash
  • Insomnia
  • Hyperglycemia

Pharmaceutical category

  • Proton Pump Inhibitor

Reconstitution instructions

  • Reconstitution and administration instructions for IV injection and IV infusion provided.

Administration precautions

  • Tablet should not be split, chewed or crushed.

Storage recommendations

  • Keep in a dry place, away from light and heat. Keep out of the reach of children.

Chemical properties

  • Molecular Formula: C16H15F2N3O4S

Therapeutic benefits

  • Suppression of acid secretion for therapeutic benefit in various gastrointestinal conditions.

Pregnancy category

  • US FDA Pregnancy Category B. Caution advised due to limited studies in pregnant women and excretion in human milk.

Mode of action

  • Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell.

Administering frequency

  • Daily administration for specified durations based on the indication.

Pharmacological effect

  • Inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus, that persists longer than 24 hours.

Pharmacological interaction

  • No significant drug interactions observed in clinical studies.

Therapy indications

  • Indicated for peptic ulcer diseases, gastroesophageal reflux diseases, ulcer induced by NSAIDs, eradication of Helicobacter pylori, and Zollinger-Ellison Syndrome.

Medication questions

  • Common questions and answers about usage, effectiveness, storage, effects on older adults, safety, side effects, pregnancy and breastfeeding, weight gain, and missed dose.

Tablet description

  • Pantobio 20 mg Tablet is a proton pump inhibitor that suppresses the final step in gastric acid production. It is used to treat various gastrointestinal conditions.

Chemical structure visual

  • Chemical structure represented by a molecular formula and visual diagram of the molecular structure.

Dosage options

  • Different dosage options provided based on the specific condition being treated, both for oral and intravenous administration.

Therapeutic application

  • Suppression of acid secretion for therapeutic benefit in various gastrointestinal conditions.

Administration caution

  • Patients cautioned against splitting, chewing or crushing the tablet to ensure proper administration.

Pregnancy and lactation considerations

  • Caution advised for pregnant and breastfeeding women due to limited studies and excretion in human milk.

Storage guidelines

  • Keep in a dry place, away from light and heat. Keep out of the reach of children to ensure proper storage.

Chemical formula

  • Molecular Formula: C16H15F2N3O4S

Potential use

  • Indicated for the treatment of specific gastrointestinal conditions as described in the product information.

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