Pregel 40 mg/vial (IV Injection)

40 mg vial: ৳ 90.00

Medicine Details

Category	Details
Generic	Pantoprazole sodium
Company	Healthcare pharmaceuticals ltd
Also available as	Pregel 20 mg tablet Pregel 40 mg tablet

Indications

Peptic ulcer diseases
Gastroesophageal reflux diseases
Ulcer induced by NSAIDs
Eradication of Helicobacter pylori
Zollinger-Ellison Syndrome

Pharmacology

Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell, leading to inhibition of both basal and stimulated gastric acid secretion.

Dosage & Administration

Oral
IV Injection

Drug Interactions

No significant drug interactions observed in clinical studies

Contraindications

Contraindicated in patients with known hypersensitivity to any of the components of the formulation

Side Effects

Headache
Diarrhea
Abdominal pain
Flatulence
Rash
Insomnia
Hyperglycemia

Pregnancy & Lactation

US FDA Pregnancy Category B, should be used during pregnancy only if clearly needed, excreted in human milk

Precautions & Warnings

Tablet should not be split, chewed or crushed
Long-term therapy may lead to malabsorption of Vitamin B12 or increase the risk of osteoporosis-related disorders

Overdose Effects

No known symptoms of overdosage in humans, not readily dialyzable

Therapeutic Class

Proton Pump Inhibitor

Reconstitution

IV injection reconstituted with 0.9% Sodium Chloride Injection, IV infusion over approximately 15 minutes, storage conditions

Storage Conditions

Keep in a dry place, away from light and heat, out of reach of children

Chemical Structure

Molecular Formula: C16H15F2N3O4S
Chemical Structure Image: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg

Common Questions

What is Pregel 40 mg/vial Injection?: Proton pump inhibitor used to treat Peptic ulcer diseases, GERD, Ulcer induced by NSAIDs, Eradication of Helicobacter pylori, Zollinger-Ellison Syndrome
How long do I need to use Pregel 40 mg/vial Injection before I see improvement in my condition?: To be taken till improvement is seen
At what frequency do I need to use Pregel 40 mg/vial Injection?: As prescribed by the doctor
Should I use Pregel 40 mg/vial Injection empty stomach, before food or after food?: Prior to the meal, approximately 30 minutes before
Storage and disposal instructions: Keep in a cool dry place in its original packaging, out of reach of children and pets
Effects on older adults: May increase the risk for bone fractures, especially with longer use, higher doses
How long does it take for Pregel 40 mg/vial Injection to work?: Improvement within 2 to 3 days, up to 4 weeks for proper effect
Is Pregel 40 mg/vial Injection safe?: Relatively safe, advised to consult the doctor before consuming
Does Pregel 40 mg/vial Injection cause weight gain?: In rare cases
What are the side effects of Pregel 40 mg/vial Injection?: Headache, diarrhea, constipation, allergic reaction
Can I take Pregel 40 mg/vial Injection if I am pregnant or breastfeeding?: Advised not to take without doctor's prescription
What should I do if I miss a dose of Pregel 40 mg/vial Injection?: Take as soon as remembered, skip if close to next dose