Exipro 40 mg (Tablet (Enteric Coated))
Medicine Details
| Category | Details |
|---|---|
| Generic | Pantoprazole sodium |
| Company | Leon pharmaceuticals ltd |
| Also available as |
Indications
- Peptic ulcer diseases
- Gastroesophageal reflux diseases
- Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
- Eradication of Helicobacter pylori (in combination with antibiotics)
- Zollinger-Ellison Syndrome
Pharmacology
Pantoprazole suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell.
Dosage & Administration
- 40 mg daily for benign gastric ulcer for 4 weeks, continued for further 4 weeks if not fully healed
- 20-40 mg daily for gastro-esophageal reflux disease for 4 weeks, continued for further 4 weeks if not fully healed
- 40 mg daily for duodenal ulcer for 2 weeks, continued for further 2 weeks if not fully healed
- 40 mg twice daily for duodenal ulcer associated with Helicobacter pylori in association with antimicrobial agents
- 20 mg daily for prophylaxis of NSAID-associated gastric or duodenal ulcer
- 80 mg once daily for Zollinger-Ellison Syndrome
- 40 mg once daily for duodenal ulcer and gastric ulcer for 7-10 days (IV Injection)
- 40 mg once daily for gastroesophageal reflux disease with a history of erosive esophagitis for 7-10 days (IV Injection)
- IV 80 mg for prevention of rebleeding in peptic ulcer, followed by 8 mg/hour infusion for 72 hours
- 80 mg for prophylaxis of acid aspiration (IV Injection)
- 80 mg IV every 12 hours for long-term management of Zollinger-Ellison Syndrome (IV Injection)
Interaction
No significant drug interactions observed in clinical studies.
Contraindications
Pantoprazole is contraindicated in patients with known hypersensitivity to any of the components of the formulation.
Side Effects
- Headache
- Diarrhea
- Abdominal pain
- Flatulence
- Rash
- Insomnia
- Hyperglycemia
Pregnancy & Lactation
US FDA Pregnancy Category B. No adequate and well-controlled studies in pregnant women. Should be used during pregnancy only if clearly needed. Excreted in human milk.
Precautions & Warnings
Exipro tablet should not be split, chewed, or crushed. Long-term therapy may lead to malabsorption of cyanocobalamin (Vitamin B12) or increase the risk of osteoporosis related disorders.
Overdose Effects
No known symptoms of overdosage in humans. Not readily dialyzable. Apart from symptomatic and supportive management, no specific therapy is recommended.
Therapeutic Class
Proton Pump Inhibitor
Reconstitution
- Exipro IV injection should be given as a slow intravenous injection
- Exipro IV infusion should be given as an intravenous infusion over a period of approximately 15 minutes
Storage Conditions
Keep in a dry place, away from light and heat. Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C16H15F2N3O4S
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg
Common Questions about Exipro 40 mg Tablet
- How long do I need to use Exipro 40 mg Tablet before I see improvement in my condition?
- At what frequency do I need to use Exipro 40 mg Tablet?
- Should I use Exipro 40 mg Tablet empty stomach, before food, or after food?
- What are the instructions for the storage and disposal of Exipro 40 mg Tablet?
- What are the effects of Exipro 40 mg Tablet on older adults?
- How long does it take for Exipro 40 mg Tablet to work?
- Is Exipro 40 mg Tablet safe?
- Does Exipro 40 mg Tablet cause weight gain?
- What are the side effects of Exipro 40 mg Tablet?
- Can I take Exipro 40 mg Tablet if I am pregnant or breastfeeding?
- What should I do if I miss a dose of Exipro 40 mg Tablet?