Tazox 500 mg (Tablet)

Unit Price: ৳ 10.03 (12's pack: ৳ 120.37)

Medicine Details

Category Details
Generic Nitazoxanide
Company Novo healthcare and pharma ltd
Also available as

Indications

  • Treatment of diarrhea caused by Cryptosporidium parvum
  • Treatment of diarrhea caused by Giardia lamblia
  • Treatment of diarrhea caused by Entamoeba histolytica

Pharmacology

  • Synthetic antiprotozoal agent for oral administration
  • Interference with the Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme
  • Inhibition of the growth of sporozoites and oocyst of Cryptosporidium parvum
  • Inhibition of the growth of trophozoites of Giardia lamblia

Dosage & Administration

  • Dosage for Age 1-3 years: 1 tea-spoonfull or 5 ml suspension every 12 hours for 3 days
  • Dosage for Age 4-11 years: 2 tea-spoonfulls or 10 ml suspension every 12 hours for 3 days
  • Dosage for Age 12 years or above: 5 tea-spoonfulls (25 ml) suspension or 1 tablet every 12 hours for 3 days
  • Recommendation to be administered with food

Interaction

  • Highly bound to plasma protein
  • Caution when administering concurrently with other highly plasma protein-bound drugs with narrow therapeutic index

Contraindications

  • Contraindicated in patients with known hypersensitivity to Nitazoxanide

Side Effects

  • Abdominal pain
  • Vomiting
  • Headache
  • Nausea
  • Anorexia
  • Flatulence
  • Increased appetite
  • Enlarged salivary glands
  • Increased creatinine & SGPT level
  • Pruritus
  • Rhinitis
  • Sweating
  • Dizziness
  • Discolored urine
  • Mild and transient nature of common side effects

Pregnancy & Lactation

  • US FDA pregnancy category B
  • No adequate and well-controlled studies in pregnant women
  • Excretion in human milk
  • Caution during lactation

Precautions & Warnings

  • Caution for patients with hepatic & biliary disease
  • Caution for patients with renal disease

Therapeutic Class

  • Anti-diarrhoeal
  • Antiprotozoal

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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