P-Lock 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (6 x 10: ৳ 300.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Pantoprazole sodium
Company One pharma ltd
Also available as
P lock 40 mg tablet

Product Title

  • P-Lock 20 mg Tablet

Categories

  • Medicine
  • Gastric Health
  • Proton Pump Inhibitor

Description

  • Pantoprazole is a proton pump inhibitor that suppresses the final step in gastric acid production
  • Used for peptic ulcer diseases, GERD, Ulcer induced by NSAIDs, Eradication of Helicobacter pylori, Zollinger-Ellison Syndrome

Dosage

  • 40 mg daily for benign gastric ulcer
  • 20-40 mg daily for GERD
  • 40 mg daily for duodenal ulcer
  • 40 mg twice daily for duodenal ulcer associated with H. pylori
  • 20 mg daily for NSAID-associated gastric or duodenal ulcer
  • 80 mg initially for Zollinger-Ellison Syndrome

Administration

  • Oral
  • IV Injection

Side Effects

  • Headache
  • Diarrhea
  • Abdominal Pain
  • Flatulence
  • Rash
  • Insomnia
  • Hyperglycemia

Interaction

  • No significant drug interactions observed in clinical studies

Contraindications

  • Known hypersensitivity to any of the components

Pregnancy Category

  • Category B (US FDA)

Precautions

  • Tablet should not be split, chewed or crushed
  • Long-term therapy may lead to malabsorption of Vitamin B12
  • May increase the risk of osteoporosis related disorders

Overdose Effects

  • No known symptoms of overdosage in humans
  • Highly protein bound, not readily dialyzable

Therapeutic Class

  • Proton Pump Inhibitor

Reconstitution

  • IV injection should be given as a slow intravenous injection
  • Reconstituted solution may be stored at room temperature for a maximum of 4 hours
  • IV infusion should be given over a period of approximately 15 minutes
  • Admixed solution may be stored at room temperature and must be used within 24 hours

Storage Conditions

  • Keep in a dry place, away from light and heat
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C16H15F2N3O4S

Indications

  • Peptic ulcer diseases
  • GERD
  • Ulcer induced by NSAIDs
  • Eradication of Helicobacter pylori
  • Zollinger-Ellison Syndrome

Pharmacology

  • Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ ATPase enzyme system

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Excreted in human milk
  • Use during pregnancy only if clearly needed

Precautions & Warnings

  • P-Lock tablet should not be split, chewed or crushed
  • Long-term therapy may lead to malabsorption of Vitamin B12
  • May increase the risk of osteoporosis related disorders

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