Paricap 1 mcg (Capsule)

Unit Price: ৳ 25.00 (1 x 10: ৳ 250.00)
Strip Price: ৳ 250.00

Medicine Details

Category Details
Generic Paricalcitol
Company Drug international ltd

Title, Categories, and Description

  • Paricap Capsules
  • Medicine
  • Thyroid Drugs & Hormone
  • Treatment of Secondary Hyperparathyroidism
  • Chronic Kidney Disease Stages 3, 4, and 5
  • Prevention and Treatment of Hyperparathyroidism
  • Vitamin D Analog
  • Pharmacological Actions Mediated through VDR
  • Oral Administration
  • Dosage Instructions
  • Dosing Frequency
  • Initial Dose based on Baseline PTH Level
  • Dose Titration based on IPTH Level
  • Monitoring of Serum Calcium and Phosphorus Levels
  • Administration Frequency
  • Interaction with Strong CYP3A Inhibitors
  • Contraindications for Hypercalcemia and Vitamin D Toxicity
  • Side Effects Caution
  • Pregnancy and Lactation Warnings
  • Precautions for Hypercalcemia and Digitalis Toxicity
  • Pediatric Use for CKD Stages 3, 4, and 5
  • Geriatric Use
  • Overdose Effects and Treatment
  • Storage Conditions

Pharmacology

  • Biologically Active Vitamin D2 Analog
  • Preclinical Studies
  • In Vitro Studies
  • Selective Activation of Vitamin D Responsive Pathways
  • Reduction of Parathyroid Hormone Levels

Dosage & Administration

  • Oral Intake
  • Administration Without Regard to Food
  • Initial Dose Based Upon Baseline PTH Level
  • Dose Titration Based Upon IPTH Level
  • Individualized Dose Titration
  • Frequency of Dosage Adjustment
  • Dosage Adjustment based on Calcium and Phosphorus Levels
  • Monitoring of Serum Calcium and Phosphorus

Interaction

  • Increase in Exposure with Strong CYP3A Inhibitors
  • Reduced Absorption if Administered with Cholestyramine or Mineral Oil

Contrindications

  • Evidence of Hypercalcemia
  • Vitamin D Toxicity

Side Effects

  • Adverse Reaction Variability

Pregnancy & Lactation

  • Insufficient Data for Pregnancy Risks
  • Risk of Birth Defects and Miscarriage
  • Absence of Information on Drug Presence in Human Milk
  • Adverse Reactions in Breastfed Infants
  • Caution Against Breastfeeding during Treatment

Precautions & Warnings

  • Hypercalcemia Caution
  • Digitalis Toxicity Potentiation
  • Special Considerations for Elderly Patients

Use in Special Populations

  • Safety and Effectiveness in Pediatric Patients
  • Pharmacokinetics in CKD Stage 5 Pediatric Patients
  • Geriatric Patient Distribution

Overdose Effects

  • Hypercalcemia
  • Hypercalciuria
  • Hyperphosphatemia
  • Suppression of PTH
  • General Supportive Measures
  • Induction of Emesis or Gastric Lavage
  • Assessment of Electrocardiographic Abnormalities
  • Therapeutic Alternatives for Elevated Serum Calcium Levels

Therapeutic Class

  • Thyroid Drugs & Hormone

Storage Conditions

  • Temperature and Humidity Control
  • Protection from Light
  • Safety Considerations for Children

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