Zoana 100 mg/5 ml (Powder for Suspension)
32 ml bottle: ৳ 35.24
Medicine Details
| Category | Details |
|---|---|
| Generic | Nitazoxanide |
| Company | Orion pharma ltd |
| Also available as |
Indications
- Treatment for diarrhea caused by Cryptosporidium parvum
- Treatment for diarrhea caused by Giardia lamblia
- Treatment for diarrhea caused by Entamoeba histolytica
Pharmacology
- Nitazoxanide is a synthetic antiprotozoal agent
- Orally administered
- Interference with Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme-dependant electron transfer reaction
- Essential for anaerobic energy metabolism of the protozoa
- Active in inhibiting the growth of sporozoites and oocyst of Cryptosporidium parvum
- Active in inhibiting the growth of trophozoites of Giardia lamblia
Dosage & Administration
- Age-based dosage - 1-3 years: 1 tea-spoonful (5 ml) every 12 hours for 3 days
- Age-based dosage - 4-11 years: 2 tea-spoonfuls (10 ml) every 12 hours for 3 days
- Age-based dosage - 12 years or above: 5 tea-spoonfuls (25 ml) or 1 tablet every 12 hours for 3 days
- Recommended to be administered with food
Interaction
- Highly bound to plasma protein
- Caution when administering concurrently with other highly plasma protein-bound drugs with narrow therapeutic index
Contraindications
- Contraindicated in patients with known hypersensitivity to Nitazoxanide or any components of the preparation
Side Effects
- Frequent side effects - abdominal pain, vomiting, headache (typically mild and transient in nature)
- Very rare side effects - nausea, anorexia, flatulence, increased appetite, enlarged salivary glands, increased creatinine & SGPT level, pruritus, rhinitis, sweating, dizziness, discolored urine
Pregnancy & Lactation
- US FDA pregnancy category - B
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if clearly needed
- Excreted in human milk
- Caution during lactation
Precautions & Warnings
- Administered with caution to patients with hepatic & biliary disease
- Administered with caution to patients with renal disease
Therapeutic Class
- Anti-diarrhoeal Antiprotozoal
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children