Nebs Plus 500 mg+65 mg (Tablet)

Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00

Medicine Details

Category Details
Generic Paracetamol caffeine
Company Ethical drugs limited

Indications

  • Headache
  • Migraine
  • Toothache
  • Neuralgia
  • Feverishness
  • Period pain
  • Sore throat
  • Backache
  • Help to reduce the temperature
  • Aches and pain of colds and flu

Pharmacology

  • Combination of Paracetamol and Caffeine
  • Analgesic and antipyretic properties
  • Weak anti-inflammatory activity
  • Caffeine is an alkaloid
  • Increases the solubility and transmembrane permeation of Paracetamol
  • Increases the pain threshold and tolerance of pain
  • Raises vessel tone in the brain
  • Beneficial for treating migraine and headache

Dosage administration

  • Adult dose: 1-2 tablets every 4-6 hours
  • Max dose: 8 tablets daily
  • Child dose: Not recommended for children below 12 years

Interaction

  • May reduce serum levels with anticonvulsants
  • May enhance the anticoagulant effect of warfarin and other coumarins
  • Accelerated absorption with metoclopramide and domperidone
  • May increase serum levels with probenecid
  • May increase serum levels of chloramphenicol
  • May reduce absorption with colestyramine within 1 hr of admin
  • May cause severe hypothermia with phenothiazine

Contraindications

  • Severe renal function impairment
  • Hepatic disease (Viral Hepatitis)
  • Known hypersensitivity to paracetamol or caffeine

Side effects

  • Mild side effects
  • Haematological reactions
  • Thrombocytopenia
  • Leukopenia
  • Pancreatitis
  • Skin rashes
  • Allergic reactions

Pregnancy lactation

Consult with doctors before taking

Precautions warnings

  • Given cautiously in hepatic or renal failure cases
  • Given cautiously in patients taking other hepatotoxic medication
  • Avoid prolonged use without consulting a physician

Overdose effects

  • Symptoms of Paracetamol overdose in the first 24 hours
  • Liver damage
  • Abnormalities of glucose metabolism
  • Metabolic acidosis

Therapeutic class

Non opioid analgesics

Storage conditions

Cool and dry place, protect from light and moisture, Keep out of reach from children

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