Zoxanid 100 mg/5 ml (Powder for Suspension)

30 ml bottle: ৳ 35.24

Medicine Details

Category	Details
Generic	Nitazoxanide
Company	Silva pharmaceuticals ltd
Also available as	Zoxanid 500 mg tablet

Indications

Diarrhea caused by Cryptosporidium parvum
Diarrhea caused by Giardia lamblia
Diarrhea caused by Entamoeba histolytica

Pharmacology

Synthetic antiprotozoal agent for oral administration
Interference with Pyruvate Ferredoxin Oxido Reductase enzyme-dependant electron transfer reaction
Inhibition of the growth of sporozoites and oocyst of Cryptosporidium parvum
Inhibition of the growth of trophozoites of Giardia lamblia

Dosage & Administration

1-3 years: 1 tea-spoonfull or 5 ml suspension every 12 hours for 3 days
4-11 years: 2 tea-spoonfulls or 10 ml suspension every 12 hours for 3 days
12 years or above: 5 tea-spoonfulls (25 ml) suspension or 1 tablet every 12 hours for 3 days
Recommended to be administered with food

Interaction

Highly bound to plasma protein
Caution when administering concurrently with other highly plasma protein-bound drugs with narrow therapeutic index

Contraindications

Known hypersensitivity to Nitazoxanide or any components of the preparation

Side Effects

Abdominal pain
Vomiting
Headache
Nausea (rare)
Anorexia (rare)
Flatulence (rare)
Increased appetite (rare)
Enlarged salivary glands (rare)
Increased creatinine & SGPT level (rare)
Pruritus (rare)
Rhinitis (rare)
Sweating (rare)
Dizziness (rare)
Discolored urine (rare)

Pregnancy & Lactation

US FDA pregnancy category B
No adequate and well-controlled studies in pregnant women
Excreted in human milk
Caution during lactation

Precautions & Warnings

Caution in patients with hepatic & biliary disease
Caution in patients with renal disease

Therapeutic Class

Anti-diarrhoeal
Antiprotozoal

Storage Conditions

Keep in a dry place away from light and heat
Keep out of the reach of children

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