Thiotab 7.5 mg (Tablet)
Unit Price: ৳ 0.46 (100's pack: ৳ 46.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Sodium thiosulfate |
| Company | Sonear laboratories ltd |
| Also available as |
Indications
- Treatment of acute cyanide poisoning
- Life-threatening situations
- Caution in uncertain diagnosis
Pharmacology
- Acts as antidote for cyanide poisoning
- Speeds up conversion of cyanide to thiocyanide
- Used in combination with sodium nitrite or alone in less severe poisoning
Dosage & Administration
- Adult dosage: 12.5 g of sodium thiosulfate over 10 min
- Child dosage: 400 mg/kg of sodium thiosulfate
- Repeat doses may be given after 30 min at half the initial doses
Interaction
- No formal drug interaction studies conducted
Side Effects
- Osmotic disturbances
- Catharsis at high doses
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy if benefit justifies risk to fetus
- Unknown excretion in human milk
Precautions & Warnings
- May contain trace impurities of sodium sulfite
- No contraindication for sulfite-sensitive patients in emergency situations
Use in Special Populations
- No clinical studies in pediatric population
- Elderly patients may have greater risk of adverse reactions
Overdose Effects
- Reduction in oxygen saturation due to rightward shift in oxygen hemoglobin dissociation curve
- Return to baseline oxygen saturations after discontinuation
Therapeutic Class
- Antidote preparations
Storage Conditions
- Store at controlled room temperature between 20°C and 25°C
- Protect from direct light
- Do not freeze