Paradil Extra 500 mg+65 mg (Tablet)
Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Paracetamol caffeine |
| Company | Biogen pharmaceuticals ltd |
Title
- Paracetamol & Caffeine Tablets
Categories
- Medicine
- Pain Relief
- Fever Reducer
- Analgesic
Description
- This medicine contains Paracetamol and Caffeine, which work together to provide relief from various conditions including headache, migraine, toothache, neuralgia, feverishness, period pain, sore throat, backache, and aches and pain of colds and flu.
Indications
- Headache
- Migraine
- Toothache
- Neuralgia
- Feverishness
- Period pain
- Sore throat
- Backache
- Help to reduce the temperature
- Aches and pain of colds and flu
Pharmacology
- Combination of Paracetamol and Caffeine
- Analgesic properties
- Antipyretic properties
- Weak anti-inflammatory activity
- Increased solubility and transmembrane permeation of Paracetamol by Caffeine
- Increased pain threshold and tolerance of pain by Caffeine
- Increased vessel tone in the brain by Caffeine
Dosage and Administration
- Adult dose: 1-2 tablets every 4-6 hours
- Maximum adult dose: 8 tablets daily
- Not recommended for children below 12 years
Interactions
- Reduction in serum levels with anticonvulsants
- Enhanced anticoagulant effect with prolonged use of warfarin and other coumarins
- Accelerated absorption with metoclopramide and domperidone
- Increased serum levels with probenecid
- Reduction in absorption with colestyramine within 1 hr of admin
- Severe hypothermia with phenothiazine
Contraindications
- Severe renal function impairment
- Hepatic disease (Viral Hepatitis)
- Known hypersensitivity to paracetamol or caffeine
Side Effects
- Mild side effects of paracetamol
- Haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis
- Pancreatitis
- Skin rashes
- Allergic reactions
Pregnancy and Lactation
- Consultation required for pregnant mothers
- Safe for breastfeeding mothers
Precautions and Warnings
- Cautious use in patients with hepatic or renal failure
- Cautious use in patients taking other hepatotoxic medication
- Avoid prolonged use without consulting a physician
Overdose Effects
- Symptoms of Paracetamol overdose in the first 24 hours
- Liver damage may become apparent 12 to 40 hours after ingestion
- Abnormalities of glucose metabolism
- Metabolic acidosis
Therapeutic Class
- Non opioid analgesics
Storage Conditions
- Cool and dry place
- Protection from light and moisture
- Keep out of the reach of children