Premol Plus 500 mg+65 mg (Tablet)
Unit Price: ৳ 1.50 (100's pack: ৳ 150.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Paracetamol caffeine |
| Company | Premier pharmaceuticals ltd |
Indications
- Headache
- Migraine
- Toothache
- Neuralgia
- Feverishness
- Period pain
- Sore throat
- Backache
- Help to reduce the temperature
- Aches and pain of colds and flu
Pharmacology
- Combination of Paracetamol and Caffeine
- Analgesic properties
- Antipyretic properties
- Weak anti-inflammatory activity
- Increases solubility and transmembrane permeation of Paracetamol
- Increases pain threshold and tolerance of pain
- Raises vessel tone in the brain
Dosage & Administration
Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily. Child dose: Not recommended for children below 12 years.
Interaction
- May reduce serum levels with anticonvulsants
- May enhance the anticoagulant effect of warfarin and other coumarins
- Accelerated absorption with metoclopramide and domperidone
- May increase serum levels with probenecid
- May increase serum levels of chloramphenicol
- May reduce absorption with colestyramine
- May cause severe hypothermia with phenothiazine
Contraindications
- Severe renal function impairment
- Hepatic disease (Viral Hepatitis)
- Known hypersensitivity to paracetamol or caffeine
Side Effects
- Mild side effects
- Haematological reactions
- Thrombocytopenia
- Leukopenia
- Pancreatitis
- Skin rashes
- Allergic reactions
Pregnancy & Lactation
Pregnant mothers should consult with doctors before taking Paracetamol & Caffeine. Can be taken whilst breast feeding.
Precautions & Warnings
- Cautious use in patients with hepatic or renal failure
- Cautious use in patients taking other hepatotoxic medication
- Avoid prolonged use without consulting a physician
Overdose Effects
- Symptoms of Paracetamol overdose in the first 24 hours
- Liver damage
- Abnormalities of glucose metabolism
- Metabolic acidosis
Therapeutic Class
Non opioid analgesics
Storage Conditions
Store in a cool and dry place, protect from light and moisture. Keep all medicines out of the reach of the children.