Temol Extra 500 mg+65 mg (Tablet)
Medicine Details
Category | Details |
---|---|
Generic | Paracetamol caffeine |
Company | Team pharmaceuticals ltd |
Indications
- Headache
- Migraine
- Toothache
- Neuralgia
- Feverishness
- Period pain
- Sore throat
- Backache
- Help to reduce the temperature
- Aches and pain of colds and flu
Pharmacology
Combination of Paracetamol and Caffeine. Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity. Caffeine increases the solubility and transmembrane permeation of Paracetamol, increases pain threshold and tolerance of pain, and raises vessel tone in the brain to treat migraine and headache.
Dosage & Administration
Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily. Child dose: Not recommended for children below 12 years.
Interaction
May reduce serum levels with anticonvulsants, enhance the anticoagulant effect of warfarin, accelerate absorption with metoclopramide and domperidone, increase serum levels with probenecid, increase serum levels of chloramphenicol, reduce absorption with colestyramine within 1 hr of admin, may cause severe hypothermia with phenothiazine.
Contraindications
Paracetamol is contraindicated in patients with severe renal function impairment and hepatic disease (Viral Hepatitis), and in those with known hypersensitivity to paracetamol or caffeine.
Side Effects
Mild side effects for paracetamol, but haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Pancreatitis, skin rashes, and allergic reactions occur occasionally.
Pregnancy & Lactation
Pregnant mothers should consult with doctors before taking Paracetamol & Caffeine. Paracetamol & Caffeine can be taken whilst breastfeeding.
Precautions & Warnings
Given cautiously in patients with hepatic or renal failure, in patients taking other hepatotoxic medication. Prolonged use without consulting a physician should be avoided.
Overdose Effects
Symptoms of Paracetamol overdose include pallor, nausea, vomiting, anorexia, abdominal pain, and liver damage. Abnormalities of glucose metabolism and metabolic acidosis may occur.
Therapeutic Class
Non opioid analgesics
Storage Conditions
Store in a cool and dry place, protect from light and moisture. Keep all medicines out of the reach of children.
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