Jardian 25 mg (Tablet)
Unit Price: ৳ 40.00 (1 x 10: ৳ 400.00)
Strip Price: ৳ 400.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Empagliflozin |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Risk reduction of cardiovascular death in type 2 diabetes mellitus patients with established cardiovascular disease
Pharmacology
Sodium glucose co-transporter-2 (SGLT-2) inhibitor
Dosage & Administration
Recommended dose: 10mg once daily, can be increased to 25mg once daily
Interactions
- Diuretics - increased urine volume
- Insulin or Insulin Secretagogues - increased risk for hypoglycemia
- Positive Urine Glucose Test - not recommended for monitoring glycemic control
- Interference with 1,5-anhydroglucitol (1,5-AG) Assay - not recommended for monitoring glycemic control
Contraindications
Severe hypersensitivity reaction, severe renal impairment, end-stage renal disease, dialysis
Side Effects
- Urinary tract infections
- Female genital mycotic infections
- Dehydration
- Hypotension
- Weakness
- Dizziness
- Increased thirstiness
Pregnancy & Lactation
- Use during pregnancy only if benefit justifies potential risk to fetus
- Not recommended when breastfeeding
Precautions & Warnings
Assessment of renal function recommended prior to initiation, no initiation in patients with eGFR less than 45 ml/min/1.73 m2
Overdose Effects
Usual supportive measures
Therapeutic Class
Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
Keep in a cool & dry place (below 30°C), protected from light & moisture, keep out of reach of children
Chemical Structure
- Molecular Formula: C23H27ClO7
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-1275-empagliflozin-chemical-structure-Z3X0mrA6UvgM682Jgp8K.svg
FAQ
- Reduces reabsorption of glucose from kidney
- Improves glycemic control in adults
- Unsafe to use during pregnancy
- Probably unsafe to use during breastfeeding
- Should be used cautiously in patients with underlying kidney disease
- No dose adjustment needed for patients with mild to moderate liver disease
- Used alone or together with other diabetes medicines to control blood sugar and avoid long-term complications
- May cause dehydration or increased urination, drink plenty of water and stay hydrated
- May cause hypoglycemia when used with other antidiabetic medicines, alcohol, or if meal is delayed or missed
- Can cause genital fungal and/or urinary tract infections, practice good hygiene
- Monitor blood sugar regularly while taking
- Inform doctor if experience constant dizziness, joint pain, cold-like symptoms, or unexplained nausea/vomiting