Actilac 3.35 gm/5 ml (Oral Solution)
Medicine Details
| Category | Details |
|---|---|
| Generic | Lactulose |
| Company | Healthcare pharmaceuticals ltd |
Title
Actilac 3.35 gm/5 ml Oral Solution
Categories
- Medicine
- Laxative
- Pharmacology
Description
Actilac is a hyperosmolar laxative which is used as an effective treatment approach for constipation. It is a non-absorbable disaccharide which draws water into the bowel; causes distention through fluid accumulation, thus promotes soft stool and accelerates bowel motion.
Indications
- Constipation
- Intestinal flora disturbances
- Increased blood ammonia levels
Pharmacology
Lactulose is a synthetic disaccharide. Lactulose is metabolized in the colon by the saccharolytic bacteria, producing low molecular weight organic acids (mainly lactic acid), which lowers the pH of the colon contents, promote the retention of water by an osmotic effect; thus increasing peristaltic activity. Lactulose is minimally absorbed; therefore, the pharmacokinetics of the absorbed material are not relevant to the principal therapeutic action.
Dosage administration
- Constipation:
- Adults: 3-6 tea-spoons daily
- Children up to 14 years: 3 tea-spoons daily
- Infants and toddlers: 1-2 tea-spoons daily
- Intestinal flora disturbances:
- Adults: 1-2 tea-spoons daily
- Children: 1 tea-spoon daily
- Reduction of blood ammonia level:
- Hyper-ammoniemia in hepatopathy: 18-30 tea-spoons daily
- In portal systemic encephalopathy: hourly doses of 6-9 tea-spoons of Lactulose solution
Interaction
There is no significant drug interactions with Actilac. The glycosidic effect of cardiac glycosides can be intensified by potassium deficiency in abuse.
Contraindications
- Hypersensitivity to either galactose and or lactose
- galactose-free diet
- gastro-cardial symptom complex
- suspected intestinal obstruction
Side effects
- Occasional flatulence
- cramp and abdominal discomfort
- Overdose can result in diarrhea
- loss of electrolytes (primarily potassium)
Pregnancy lactation
US FDA Pregnancy Category of Lactulose is B. Studies show that Lactulose has no adverse effects. Decisions regarding use during pregnancy and lactation must be made by registered physician.
Precautions warnings
Actilac should be administered with care to patients who are intolerant to Actilac. The dose used in the treatment of (pre) coma hepaticum is usually much higher and may need to be taken into consideration for diabetics.
Overdose effects
There have been no reports of accidental overdosage. In the event of acute overdosage it is expected that diarrhea and abdominal cramps would be the major symptoms.
Therapeutic class
Osmotic purgatives
Storage conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
Chemical structure
- Molecular formula: C12H22O11
- Chemical structure: https://medex.com.bd/storage/res/g-res-653-lactulose-chemical-structure-LBdJlB1MefGyTS21429X.svg
Commonly asked questions
- What is the use of Actilac 3.35 gm/5 ml Solution?
- At what frequency do I need to use Actilac 3.35 gm/5 ml Solution?
- How long does it take for Actilac 3.35 gm/5 ml Solution to work?
- What is Actilac 3.35 gm/5 ml Solution used for?
- Is Actilac 3.35 gm/5 ml Solution a laxative?
- What are the side effects of taking Actilac 3.35 gm/5 ml Solution?
- Is it okay to take Actilac 3.35 gm/5 ml Solution every day?
- Who should not be given Actilac 3.35 gm/5 ml Solution?
- What if I take more than the recommended dose of Actilac 3.35 gm/5 ml Solution?
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