Povidex 5% w/w (Ointment)

25 gm tube: ৳ 55.00

Medicine Details

Indications

  • Adjunct to systemic therapy for primary or secondary topical infections
  • Treatment of infected surgical incisions
  • Treatment of infected decubitus or stasis ulcers
  • Treatment of pyodermas
  • Treatment of secondarily infected dermatoses
  • Prevention of microbial contaminations in burns, incisions, and other topical lesions
  • Treatment of seborrhea
  • Preoperative and postoperative scrubbing and washing of hospital operating room and equipment
  • Disinfection of wounds, burns, lacerations, and abrasions
  • Prophylactic anti-infective agent in house, hospital & office procedures
  • Postoperative application to incisions to help prevent infection
  • Treatment of oral moniliasis (thrush); bacterial and mycotic skin infections
  • Preoperative swab in the mouth & throat
  • Treatment of acute mucosal infections of the mouth and pharynx
  • Oral hygiene prior to, during, and after dental and oral surgery
  • Symptomatic treatment of dry eye conditions including keratoconjunctivitis sicca

Pharmacology

  • Complex of iodine and an organic polymer
  • Prolongs germicidal activity of iodine by liberating elemental iodine slowly
  • Rapid microbicidal activity against Gram-positive and Gram-negative bacteria, protozoa, viruses, and fungi/yeasts
  • Sporicidal
  • Non-staining
  • Active in the presence of soap, blood, serum, pus, mucosal secretions, and water

Dosage & Administration

  • Apply once or twice daily for a maximum of 14 days for the treatment of infection
  • Apply once or twice a week for the prevention of infection
  • Gargle or rinse with up to 10 mL for up to 30 seconds without swallowing, repeat up to four times daily for up to 14 consecutive days
  • Wet hands and forearms with water, apply Povidone Iodine Surgical Scrub and spread over both hands and forearms, scrub thoroughly for about five minutes

Interaction

  • Exhibits interaction with strong alkali, sodium thiosulphate, sodium metabisulphite, and thiomersal
  • Concurrent lithium therapy may lead to hypothyroidic effect

Contraindications

  • Causes hypersensitivity reactions
  • Avoid regular use in patients with thyroid disorders or those receiving lithium therapy
  • Not for use in serious cavities and in children under the age of 2 years

Side Effects

  • May cause hypersensitivity reactions and irritation of the skin and mucous membranes
  • Application to severe burns or large denuded areas may produce systemic adverse effects such as metabolic acidosis, hypernatraemia, and impairment of renal function
  • May interfere with thyroid function tests

Pregnancy & Lactation

  • Not recommended for use during pregnancy due to possible absorption affecting the fetal thyroid
  • Considered usually compatible with breastfeeding by the American Academy of Pediatrics

Precautions & Warnings

  • In case of deep or puncture wounds or serious burns, consult Registered Physician
  • Avoid prolonged use as it may lead to the absorption of a significant amount of iodine
  • Special caution is needed when regular applications are made to patients with pre-existing renal insufficiency
  • Avoid regular use in patients on concurrent lithium therapy
  • Care must be taken when used on known iodine sensitivity
  • Patients experiencing blurred vision after application should not drive or use machinery

Therapeutic Class

  • Iodine compounds (Anti-septic Preparations)

Storage Conditions

  • Store below 25°C
  • Do not freeze
  • Store in a cool and dry place, protected from light
  • Keep out of the reach of children
  • Do not touch the ophthalmic solution dropper tip to any surface
  • Do not use it after one month of the first opening

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