Comfort 3.35 gm/5 ml (Oral Solution)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Lactulose
Company Apc pharma ltd

Indications

  • Constipation (Chronic Constipation)
  • Intestinal flora disturbances
  • Increased blood ammonia levels (hyper ammoniemia in hepatopathy, portal-systemic encephalopathy)

Description

  • Hyperosmolar laxative
  • Non-absorbable disaccharide
  • Promotes soft stool
  • Accelerates bowel motion

Pharmacology

  • Synthetic disaccharide
  • Metabolized in the colon by saccharolytic bacteria
  • Produces low molecular weight organic acids
  • Lowers pH of colon contents
  • Promotes retention of water by osmotic effect
  • Increases peristaltic activity
  • Minimally absorbed

Dosage & Administration

  • Adult dosage
  • Children dosage
  • Infants and toddlers dosage
  • Dosage for damaged intestinal flora
  • Dosage for reduction of blood ammonia level

Interaction

  • No significant drug interactions
  • Intensified glycosidic effect of cardiac glycosides by potassium deficiency

Contraindications

  • Hypersensitivity to galactose and lactose
  • Galactose-free diet
  • Gastro-cardial symptom complex
  • Suspected intestinal obstruction

Side Effects

  • Flatulence
  • Cramp
  • Abdominal discomfort
  • Diarrhoea (overdose)
  • Loss of electrolytes, primarily potassium (overdose)

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • No adverse effects observed

Precautions & Warnings

  • Careful administration to patients intolerant to Comfort
  • Higher dose for (pre)coma hepaticum, consideration for diabetics

Overdose Effects

  • Expected symptoms: Diarrhoea, abdominal cramps

Therapeutic Class

  • Osmotic purgatives

Storage Conditions

  • Dry place away from light and heat
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C12H22O11
  • Chemical Structure: Image available

Common Questions

  • Use of Comfort 3.35 gm/5 ml Solution
  • Frequency of use
  • Time for treatment to work
  • Purpose of Comfort 3.35 gm/5 ml Solution
  • Laxative properties
  • Side effects
  • Daily usage
  • Restrictions on usage
  • Effects of overdose

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