Conlax 3.35 gm/5 ml (Oral Solution)

100 ml bottle: ৳ 140.00

Medicine Details

Category Details
Generic Lactulose
Company Unimed unihealth pharmaceuticals ltd

Title

Conlax 3.35 gm/5 ml Oral Solution

Categories

  • Medicine
  • Laxative
  • Digestive Health

Description

Conlax is a hyperosmolar laxative used for the treatment of constipation. It is a non-absorbable disaccharide that draws water into the bowel, causing distention and promoting soft stool and bowel motion.

Indications

  • Constipation
  • Intestinal flora disturbances
  • Increased blood ammonia levels

Pharmacology

Lactulose is a synthetic disaccharide metabolized in the colon by saccharolytic bacteria, promoting water retention and increasing peristaltic activity. It is minimally absorbed, with pharmacokinetics not relevant to the principal therapeutic action.

DosageAndAdministration

  • Constipation-Chronic:
    • Adults:
      • 3-6 teaspoons initially
      • 1.5-6 teaspoons daily in long-term therapy
    • Children up to 14 years:
      • 3 teaspoons initially
      • 1-2 teaspoons daily in long-term therapy
    • Infants and toddlers:
      • 1-2 teaspoons initially
      • 1 teaspoon daily in long-term therapy
  • IntestinalFloraDisturbances:
    • Adults: 1-2 teaspoons daily
    • Children: 1 teaspoon daily
  • BloodAmmoniaLevelReduction:
    • Hyper-ammoniemia in hepatopathy: 18-30 teaspoons daily
    • Portal systemic encephalopathy: hourly doses of 6-9 teaspoons, adjust after achieving the desired effect

Interaction

No significant drug interactions with Conlax. Potassium deficiency can intensify the glycosidic effect of cardiac glycosides.

Contraindications

  • Hypersensitivity to galactose and/or lactose
  • Galactose-free diet
  • Gastro-cardial symptom complex
  • Suspected intestinal obstruction

SideEffects

  • Flatulence
  • Cramps
  • Abdominal discomfort
  • Potential for diarrhea and loss of electrolytes, primarily potassium in case of overdose

PregnancyAndLactation

US FDA Pregnancy Category B. Decisions regarding use during pregnancy and lactation should be made by a registered physician.

PrecautionsAndWarnings

Administer with care to patients intolerant to Conlax. Higher doses may be needed for the treatment of (pre)coma hepaticum, which should be considered for diabetics.

OverdoseEffects

No reports of accidental overdosage. Expected symptoms include diarrhea and abdominal cramps.

TherapeuticClass

Osmotic purgatives

StorageConditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

ChemicalStructure

  • MolecularFormula: C12H22O11
  • ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-653-lactulose-chemical-structure-LBdJlB1MefGyTS21429X.svg

CommonQuestions

  • Use: To treat constipation and reduce blood ammonia in liver disease patients.
  • Frequency: Once a day for constipation, three or four times a day for liver disease.
  • TimeToWork: 2-3 days for beneficial effects. Consult a doctor if constipation persists.
  • SideEffects: Diarrhea, flatulence, nausea, vomiting, abdominal pain. Higher doses can cause diarrhea and abdominal pain.
  • UsageDuration: As advised by a doctor, up to a week for constipation.
  • NotFor: Patients allergic to Conlax or intolerant to lactose.
  • OverdoseEffects: Abdominal pain, electrolyte imbalance, diarrhea.

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