Prazopress ER 2.5 mg (Tablet (Extended Release))

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Prazosin hydrochloride
Company Unimed unihealth pharmaceuticals ltd
Also available as
Prazopress 1 mg tablet Prazopress 2 mg tablet Prazopress er 5 mg tablet

Indications

  • Treatment of essential (primary) hypertension
  • Treatment of secondary hypertension
  • Treatment of left ventricular failure
  • Treatment of Raynaud's phenomenon and Raynaud's disease
  • Adjunct in the symptomatic treatment of urinary obstruction caused by benign prostatic hyperplasia

Pharmacology

  • Decrease in total peripheral vascular resistance
  • Selective inhibition of postsynaptic alpha-1-adrenoreceptors
  • Reduction in left ventricular filling pressure
  • Reduction in cardiac impedance
  • Augmentation of cardiac output

Dosage & Administration

  • Initial therapy with a low starting dose
  • Daily dosage adjustment based on patient's response
  • Recommended starting dosage for left ventricular failure
  • Recommended starting dosage for Raynaud's phenomenon and Raynaud's disease
  • Recommended starting dosage for benign prostatic hyperplasia

Interaction

  • No adverse drug interactions reported
  • Compatible with cardiac glycosides, hypoglycemic agents, tranquilizers, sedatives, antiarrhythmic agents, and analgesic/anti-inflammatory agents

Contraindications

  • Known sensitivity to quinazolines

Side Effects

  • Dizziness
  • Headache
  • Drowsiness
  • Weakness
  • Palpitations
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Liver function abnormalities
  • Edema

Pregnancy & Lactation

  • No teratogenic effects observed in animal testing
  • Use during pregnancy only if potential benefit justifies potential risk
  • Excretion in small amounts in human milk

Precautions & Warnings

  • Postural hypotension
  • Avoid situations where injury could result from dizziness or weakness
  • Careful adjustment of diuretic dosage in left ventricular failure patients
  • Careful monitoring of blood pressure during administration in Raynaud's phenomenon, Raynaud's disease, and benign prostatic hyperplasia

Use in Special Populations

  • Not recommended for children under 12 years
  • Not recommended in left ventricular failure due to mechanical obstruction
  • Adequate data not available for left ventricular failure due to recent myocardial infarction

Overdose Effects

  • Profound drowsiness and depressed reflexes
  • Support of the cardiovascular system is of first importance
  • Renal function should be monitored and supported as needed

Therapeutic Class

  • Alpha adrenoceptor blocking drugs

Storage Conditions

  • Store away from light and moisture
  • Store below 30°C
  • Keep away from reach of children

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