Prazopress ER 5 mg (Tablet (Extended Release))

Unit Price: ৳ 17.00 (3 x 10: ৳ 510.00)
Strip Price: ৳ 170.00

Medicine Details

Category Details
Generic Prazosin hydrochloride
Company Unimed unihealth pharmaceuticals ltd
Also available as
Prazopress 1 mg tablet Prazopress 2 mg tablet Prazopress er 25 mg tablet

Indications

  • Treatment of hypertension
  • Treatment of left ventricular failure
  • Treatment of Raynaud's phenomenon and disease
  • Symptomatic treatment of urinary obstruction caused by benign prostatic hyperplasia

Pharmacology

  • Decrease in total peripheral vascular resistance
  • Lowering blood pressure in hypertensive patients
  • Reduction in left ventricular filling pressure
  • Improvement in urinary pressure profile in men

Dosage & Administration

  • Toleration is best when therapy is initiated with a low starting dose
  • Dose adjustment based on patient's response
  • Recommended starting dose for left ventricular failure
  • Recommended starting dosage for Raynaud's phenomenon and disease
  • Recommended starting dose for benign prostatic hyperplasia
  • Prazosin XR Extended-Release Tablets should be swallowed whole

Interaction

  • No adverse drug interaction reported with cardiac-glycosides, hypoglycemic agents, tranquilizers, antiarrhythmic agents, and analgesics

Contraindications

  • Known sensitivity to quinazolines

Side Effects

  • Dizziness
  • Headache
  • Drowsiness
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Liver function abnormalities
  • Edema
  • Orthostatic hypotension
  • Blurred vision
  • Hallucinations
  • Depression
  • Rash
  • Pruritus
  • Urinary frequency
  • Impotence
  • Incontinence
  • Priapism
  • Dry mouth
  • Nasal congestion
  • Fever
  • Arthralgia

Pregnancy & Lactation

  • No teratogenic effects seen in animal testing
  • Excreted in small amounts in human milk
  • Caution advised when administered to nursing mothers

Precautions & Warnings

  • Postural hypotension
  • Monitoring of blood pressure during administration
  • Careful adjustment of diuretic dosage in left ventricular failure patients

Use in Special Populations

  • Not recommended for children under 12 years
  • Not recommended in left ventricular failure due to mechanical obstruction

Overdose Effects

  • Profound drowsiness and depressed reflexes reported in accidental ingestion by a child
  • No decrease in blood pressure noted

Therapeutic Class

Alpha adrenoceptor blocking drugs

Storage Conditions

Store below 30°C, away from light and moisture, keep away from reach of children

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