Pregavax 50 mg (Capsule)

Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00

Medicine Details

Category Details
Generic Pregabalin
Company Centeon pharma ltd
Also available as
Pregavax 75 mg capsule

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues

Dosage

  • Maximum recommended dose of Pregabalin is 100 mg three times a day for adult patients with diabetic peripheral neuropathy (DPN)
  • Recommended dose for postherpetic neuralgia (PHN) is 75 to 150 mg two times a day or 50 to 100 mg three times a day
  • Recommended dose for fibromyalgia is 300 to 450 mg/day
  • Recommended dose range for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day

Administration

  • Route of administration: oral route
  • Pregabalin CR tablet should be administered after an evening meal
  • Should be swallowed whole and should not be split, crushed, or chewed

Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Common side effects in adults include dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, and thinking abnormal
  • Most common side effects in pediatric patients for the treatment of partial onset seizures are increased weight and increased appetite

Pregnancy & Lactation

  • No adequate and well-controlled studies with pregabalin in pregnant women
  • Small amounts of pregabalin have been detected in the milk of lactating women

Precautions & Warnings

  • Angioedema can occur and may be associated with life-threatening respiratory compromise requiring emergency treatment
  • Pregavax should be discontinued immediately in case of hypersensitivity reactions
  • Increases the risk of suicidal thoughts or behavior
  • May cause dizziness, somnolence, and impair patient's ability to drive or operate machinery

Use in Special Populations

  • Safety and effectiveness in pediatric patients have not been established
  • Safety and effectiveness in pediatric patients below the age of 1 month have not been established
  • Safety and effectiveness of Pregavax extended-release tablet in pediatric patients have not been established

Overdose Effects

  • Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, and restlessness

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C), protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C8H17NO2

Common Questions

  • Information about Pregavax 50 mg Capsule, its usage, dosage, storage, and side effects

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