Pregacap 75 mg (Capsule)
Unit Price: ৳ 16.00 (3 x 10: ৳ 480.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Concord pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
- Anti-nociceptive and antiseizure effects
Dosage
- Maximum recommended dose of 100 mg three times a day
- Dosing should begin at 50 mg three times a day
- Recommended dose for postherpetic neuralgia is 75 to 150 mg two times a day or 50 to 100 mg three times a day
- Recommended dose for fibromyalgia is 300 to 450 mg/day
- Recommended dose range for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
- Swallowed whole and should not be split, crushed or chewed
Drug Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
- No interaction with food and others
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Common side effects in adults include dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, and thinking abnormal
- Increased weight and increased appetite in pediatric patients
Pregnancy & Lactation
- No adequate and well-controlled studies with pregabalin in pregnant women
- Small amounts of pregabalin detected in the milk of lactating women
- Breastfeeding not recommended during treatment with pregabalin
Precautions & Warnings
- Angioedema can occur and may be associated with life-threatening respiratory compromise
- Patients need to be monitored for suicidal thoughts or behavior
- Respiratory depression may occur with concomitant CNS depressants
- May cause dizziness and somnolence and impair patients' ability to drive or operate machinery
Use in Special Populations
- Safety and effectiveness not established for pediatric patients for certain indications
- Safety and effectiveness of Pregabalin extended-release tablet not established in pediatric patients
Overdose Effects
- Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
- No specific antidote
- General supportive care required
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions about Pregacap 75 mg Capsule
- First-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
- Duration of use depends on the improvement in health conditions
- Should be taken after food in a prescribed dosage
- Storage instructions for keeping it in a cool dry place and in its original packaging
- Works differently for different diseases
- Duration of use depends on the condition for which it is consumed
- Should not be stopped abruptly without consulting a doctor
- Can be used together with Diazepam
- May cause weight gain
- Quick tips for usage and precautions