PG 25 mg (Capsule)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
- Anti-nociceptive and antiseizure effects
Dosage
- Maximum recommended dose is 100 mg three times a day (300 mg/day) for DPN
- Recommended dose is 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day) for PHN
- Recommended dose is 300 to 450 mg/day for fibromyalgia
- Recommended dose range is 150 to 600 mg/day for neuropathic pain associated with spinal cord injury
Administration
- Oral route of administration
- Can be taken with or without food
- Swallowed whole for Pregabalin CR tablet
- Should not be split, crushed or chewed
Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Difficulty with concentration/attention
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
- Breastfeeding is not recommended
Precautions & Warnings
- Angioedema can occur and may be associated with life-threatening respiratory compromise
- PG should be discontinued immediately in these cases
- Increased risk of suicidal thoughts or behavior
- Respiratory depression may occur when used with concomitant CNS depressants
- May impair patients' ability to drive or operate machinery
- Withdrawn gradually over a minimum of 1 week
Use in Special Populations
- Safety and effectiveness not established in pediatric patients for certain conditions
- Safety and effectiveness not established in pediatric patients below the age of 1 month for adjunctive therapy for partial onset seizures
- Safety and effectiveness of PG extended-release tablet not established in pediatric patients
Overdose Effects
- Reduced consciousness
- Depression/anxiety
- Confusional state
- Agitation and restlessness
- Seizures and heart block reported
- No specific antidote
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions
- What is PG 25 mg Capsule?
- How long do I need to use PG 25 mg Capsule before I see improvement in my condition?
- At what frequency do I need to use PG 25 mg Capsule?
- Should I use PG 25 mg Capsule empty stomach, before food or after food?
- What are the instructions for the storage and disposal of PG 25 mg Capsule?
- Does PG 25 mg Capsule work in the same way for each disease?
- How long do I need to take PG 25 mg Capsule?
- Is it necessary to continue taking PG 25 mg Capsule even if I feel fine?
- Can I take Diazepam and PG 25 mg Capsule together?
- Can the use of PG 25 mg Capsule cause weight gain?
Quick Tips about PG 25 mg Capsule
- Take as per the dose and duration prescribed by your doctor
- May cause sleepiness, do not drive or operate machinery until you know how it affects you
- May cause blurring or loss of vision, inform your doctor immediately if you notice any changes
- Do not stop taking PG 25 mg Capsule suddenly without talking to your doctor