Vaxar 50 mg (Capsule)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Nuvista pharma ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacological Properties
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
- Mechanism of action not fully elucidated
- Results in animal studies suggest anti-nociceptive and antiseizure effects
Dosage
- Maximum recommended dose of Pregabalin is 100 mg three times a day for DPN
- Recommended dose of Pregabalin is 75 to 150 mg two times a day for PHN
- Recommended dose of Pregabalin is 300 to 450 mg/day for fibromyalgia
- Recommended dose range of Pregabalin is 150 to 600 mg/day for spinal cord injury
- Recommended starting dose of Pregabalin CR capsule is 165 mg once daily
Route of Administration
- Oral route
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
Drug Interactions
- Unlikely to be involved in significant pharmacokinetic drug interactions
- Not applicable for drug interaction with food and others
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Common side effects in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain and thinking abnormalities
- Common side effects in pediatric patients: increased weight and increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
- Breastfeeding is not recommended due to potential risk of tumorigenicity
Precautions & Warnings
- Angioedema can occur and may be associated with life threatening respiratory compromise requiring emergency treatment
- Discontinue immediately in case of hypersensitivity reactions
- Antiepileptic drugs increase the risk of suicidal thoughts or behavior
- Respiratory depression may occur when used with concomitant CNS depressants or in the setting of underlying respiratory impairment
- May cause dizziness and somnolence, impairing ability to drive or operate machinery
- Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
- Caution should be exercised when coadministering with thiazolidinedione antidiabetic agents
Use in Special Populations
- Safety and effectiveness not established in pediatric patients for various conditions
Overdose Effects
- Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
- No specific antidote
- Supportive care indicated including monitoring of vital signs
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
FAQs
- What is Vaxar 50 mg Capsule?
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- Does Vaxar 50 mg Capsule work in the same way for each disease?
- How long do I need to take Vaxar 50 mg Capsule?
- Is it necessary to continue taking Vaxar 50 mg Capsule even if I feel fine?
- Can I take Diazepam and Vaxar 50 mg Capsule together?
- Can the use of Vaxar 50 mg Capsule cause weight gain?
- Quick Tips for taking Vaxar 50 mg Capsule