Nepco 25 mg (Capsule)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site
- Mechanism of action not fully elucidated
Dosage
- Maximum recommended dose of 100 mg three times a day for DPN
- Recommended dose of 75 to 150 mg two times a day or 50 to 100 mg three times a day for PHN
- Recommended dose of 300 to 450 mg/day for fibromyalgia
- Recommended dose range of 150 to 600 mg/day for spinal cord injury
- Dosing for pediatric patients
- Conversion from Pregabalin capsules to Pregabalin CR capsule tablet
- Pregabalin tablet total daily dose
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
- No significant food and other drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Difficulty with concentration/attention
- Increased weight and increased appetite in pediatric patients
Pregnancy lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
- Breastfeeding not recommended
Precautions warnings
- Risk of angioedema and associated respiratory compromise
- Risk of hypersensitivity reactions
- Increased risk of suicidal thoughts or behavior
- Potential respiratory depression
- Impairment of driving or operating machinery
- Increased seizure frequency if rapidly discontinued
- Potential for peripheral edema
- Caution when coadministering with thiazolidinedione antidiabetic agents
Use in special populations
- Safety and effectiveness not established in pediatric patients for several indications
- Safety and effectiveness not established for patients below the age of 1 month
Overdose effects
- Reduced consciousness
- Depression/anxiety
- Confusional state
- Agitation and restlessness
- Seizures
- Heart block
- No specific antidote
Therapeutic class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children
Chemical structure
- Molecular Formula: C8H17NO2
- Chemical Structure Image: link to image
Common questions
- What is Nepco 25 mg Capsule?
- How long do I need to use Nepco 25 mg Capsule before I see improvement in my condition?
- At what frequency do I need to use Nepco 25 mg Capsule?
- Should I use Nepco 25 mg Capsule empty stomach, before food or after food?
- Instructions for the storage and disposal
- Does Nepco 25 mg Capsule work in the same way for each disease?
- How long do I need to take Nepco 25 mg Capsule?
- Is it necessary to continue taking Nepco 25 mg Capsule even if I feel fine?
- Can I take Diazepam and Nepco 25 mg Capsule together?
- Can the use of Nepco 25 mg Capsule cause weight gain?
- Quick Tips