Nepco 75 mg (Capsule)

Unit Price: ৳ 19.00 (3 x 10: ৳ 570.00)
Strip Price: ৳ 190.00

Medicine Details

Title

  • Nepco 75 mg Capsule

Categories

  • Anticonvulsant
  • Neurotic Pain Relief
  • Shingles Treatment
  • Seizure Management
  • Fibromyalgia Treatment

Description

  • Nepco is indicated for neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, adjunctive therapy for partial-onset seizures, fibromyalgia, and neuropathic pain associated with spinal cord injury.
  • Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
  • Dosage varies based on indication and patient's condition, ranging from 75 mg to 660 mg daily.

Color Options

  • Not applicable

Function

  • Pain relief for neuropathic conditions
  • Seizure control
  • Management of fibromyalgia

Materials

  • Active ingredient: Pregabalin
  • Capsule shell components

Technical Specifications

  • Molecular Formula : C8H17NO2

Design Elements

  • Capsule form
  • CR tablet form

Usability Features

  • Route of administration: Oral
  • Can be taken with or without food

Dimensions

  • Capsule size and shape
  • CR tablet size and shape

Dosage

  • Maximum recommended dose of Pregabalin is 100 mg three times a day for DPN
  • Recommended dose for PHN is 75 to 150 mg two times a day or 50 to 100 mg three times a day
  • Recommended dose for fibromyalgia is 300 to 450 mg/day
  • Recommended dose range for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day

Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions
  • No significant drug interaction with food

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Common side effects in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, thinking abnormal
  • Common side effects in pediatric patients: increased weight, increased appetite

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Small amounts detected in the milk of lactating women
  • Breastfeeding not recommended due to potential risk of tumorigenicity

Precautions & Warnings

  • Risk of angioedema and respiratory compromise
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression may occur when used with concomitant CNS depressants
  • May cause dizziness and somnolence, impacting ability to drive or operate machinery
  • Caution needed when coadministering with thiazolidinedione antidiabetic agents

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients for certain indications
  • Safety and effectiveness not established for pediatric patients below the age of 1 month for adjunctive therapy for partial onset seizures
  • Safety and effectiveness of Nepco extended-release tablet not established in pediatric patients

Overdose Effects

  • Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, heart block
  • No specific antidote
  • General supportive care indicated including monitoring of vital signs and observation of the clinical status of the patient

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

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