SB-Gabalin 50 mg (Capsule)

Unit Price: ৳ 12.00 (50's pack: ৳ 600.00)

Medicine Details

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site

Dosage

  • Maximum recommended dose of Pregabalin for diabetic peripheral neuropathy is 100 mg three times a day
  • Recommended dose of Pregabalin for postherpetic neuralgia is 75 to 150 mg two times a day
  • Recommended dose of Pregabalin for fibromyalgia is 300 to 450 mg/day
  • Dosage for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day

Administration

  • Route of administration: oral
  • Pregabalin CR tablet should be administered after an evening meal

Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side effects

  • Most common side effects in adults are dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, and thinking abnormalities
  • Most common side effects in pediatric patients for the treatment of partial onset seizures are increased weight and increased appetite

Pregnancy and lactation

  • Potential risk to a fetus. Breastfeeding not recommended during treatment

Precautions and warnings

  • Angioedema may occur and require immediate discontinuation
  • Hypersensitivity reactions may occur and require immediate discontinuation
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression may occur when used with concomitant CNS depressants
  • May cause dizziness, somnolence, and impair ability to drive or operate machinery
  • Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
  • May cause peripheral edema
  • Exercise caution when coadministering with thiazolidinedione antidiabetic agents

Use in special populations

  • Safety and effectiveness in pediatric patients have not been established for certain conditions

Overdose effects

  • Signs and symptoms include reduced consciousness, depression/anxiety, and seizures

Therapeutic class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage conditions

  • Keep in a cool & dry place (below 30°C), protected from light & moisture

Chemical structure

  • Molecular Formula: C8H17NO2

Commonly asked questions

  • SB-Gabalin 50 mg Capsule is an anticonvulsant and is considered to be the first-line of treatment for neurotic pain, shingles, seizures, and fibromyalgia
  • Duration of use depends on the condition for which it is being used

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