Nerfid 50 mg (Capsule)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Pregabalin
Company The white horse pharmaceuticals ltd
Also available as
Nerfid 75 mg capsule Nerfid 25 mg capsule Nerfid 150 mg capsule

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds to the alpha2-delta site in central nervous system tissues

Dosage

  • Maximum recommended dose of 100 mg three times a day for neuropathic pain associated with diabetic peripheral neuropathy in adults (DPN)
  • Recommended dose of 75 to 150 mg two times a day for postherpetic neuralgia in adults (PHN)
  • Recommended dose of 300 to 450 mg/day for management of fibromyalgia in adults
  • Recommended dose range of 150 to 600 mg/day for neuropathic pain associated with spinal cord injury in adults

Administration

  • Oral route of administration
  • Can be taken with or without food
  • Pregabalin CR tablet should be administered after an evening meal
  • Should be swallowed whole and not be split, crushed or chewed

Drug Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Difficulty with concentration/attention

Pregnancy & Lactation

  • No adequate and well-controlled studies with pregabalin in pregnant women
  • Potential risk to a fetus
  • Breastfeeding is not recommended during treatment with pregabalin

Precautions & Warnings

  • Angioedema can occur and may be associated with life threatening respiratory compromise
  • Antiepileptic drugs, including Nerfid, increase the risk of suicidal thoughts or behavior
  • Respiratory depression may occur with Nerfid when used with concomitant CNS depressants
  • Nerfid may cause dizziness and somnolence
  • Increased seizure frequency or other adverse reactions may occur if Nerfid is rapidly discontinued
  • Caution should be exercised when coadministering Nerfid and thiazolidinedione antidiabetic agents

Use in Special Populations

  • Safety and effectiveness in pediatric patients have not been established for various conditions
  • Safety and effectiveness of Nerfid extended-release tablet in pediatric patients have not been established

Overdose Effects

  • Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
  • No specific antidote

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

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