Virine 3% (Ophthalmic Ointment)
5 gm tube: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Acyclovir ophthalmic |
| Company | Nipa pharmaceuticals ltd |
Indications
- Treatment of Herpes simplex keratitis
Pharmacology
- Antiviral agent
- Highly active against Herpes simplex (HSV) types I and II and Varicella zoster viruses
- Low toxicity to mammalian cells
- Phosphorylated to the active compound Acyclovir triphosphate after entry into herpes infected cell
- Acts as an inhibitor of and substrate for the herpes specific DNA polymerase
Dosage & Administration
- Same dosage for all age groups
- 10 mm ribbon of the ointment should be placed inside the lower conjunctival sac five times a day at approximately four hourly intervals
- Treatment should continue for at least 3 days after healing
Interaction
- No clinically significant interactions identified
Contraindications
- Hypersensitivity to Acyclovir or Valacyclovir
Side Effects
- Very common: Superficial punctate keratopathy
- Common: Transient mild stinging of the eye, conjunctivitis
- Rare: Blepharitis
Pregnancy & Lactation
- Pregnancy category B
- No adequate and well-controlled studies of Acyclovir in pregnant women
- Unknown excretion of topically applied Acyclovir in breast milk
Precautions & Warnings
- Recommended dosage, frequency of applications, and length of treatment should not be exceeded
Overdose Effects
- No adverse effects expected if the entire contents of the tube containing 90 mg Virine were ingested orally
Therapeutic Class
- Ophthalmic Anti-viral Products
Storage Conditions
- Store in a cool and dry place
- Keep away from light
- Keep out of reach of children
- Do not touch the tip of the tube since this may contaminate the product
- Do not use the medicine of tube after one month of opening