Leaxe 3.35 gm/5 ml (Oral Solution)
Medicine Details
| Category | Details |
|---|---|
| Generic | Lactulose |
| Company | Alco pharma ltd |
Title
Leaxe 3.35 gm/5 ml Oral Solution
Categories
- Medicines
- Laxatives
- Hyperosmolar Laxatives
Description
Leaxe is a hyperosmolar laxative which is used as an effective treatment approach for constipation. It is a non-absorbable disaccharide which draws water into the bowel; causes distention through fluid accumulation, thus promotes soft stool and accelerates bowel motion.
Indications
- Chronic Constipation
- Intestinal Flora Disturbances
- Increased Blood Ammonia Levels
Pharmacology
Lactulose is a synthetic disaccharide. Lactulose is metabolized in the colon by the saccharolytic bacteria, producing low molecular weight organic acids (mainly lactic acid), which lowers the pH of the colon contents, promote the retention of water by an osmotic effect, thus increasing peristaltic activity. Lactulose is minimally absorbed; therefore, the pharmacokinetics of the absorbed material are not relevant to the principal therapeutic action.
Dosage & Administration
- Adults: 3-6 tea-spoons daily initially
- Children up to 14 years: 3 tea-spoons daily initially
- Infants and toddlers: 1-2 tea-spoons daily initially
- For reduction of blood ammonia levels: maximum 18-30 tea-spoons daily in hyper-ammoniemia in hepatopathy
Interaction
There is no significant drug interactions with Leaxe. The glycosidic effect of cardiac glycosides can be intensified by potassium deficiency in abuse.
Contraindications
- Hypersensitivity to galactose and/or lactose
- Galactose-free diet
- Gastro-cardial symptom complex
- Suspected intestinal obstruction
Side Effects
- Occasional flatulence
- Cramps
- Abdominal discomfort
- Diarrhoea in overdose
- Loss of electrolytes, primarily potassium in abuse
Pregnancy & Lactation
US FDA Pregnancy Category B. Studies show that Lactulose has no adverse effects. Decisions regarding use during pregnancy and lactation must be made by a registered physician.
Precautions & Warnings
- Leaxe should be administered with care to patients who are intolerant to Leaxe
- Consideration needed for diabetics in (pre) coma hepaticum treatment
Overdose Effects
There have been no reports of accidental overdosage. In the event of acute overdosage, it is expected that diarrhoea and abdominal cramps would be the major symptoms.
Therapeutic Class
Osmotic purgatives
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C12H22O11
- Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-653-lactulose-chemical-structure-LBdJlB1MefGyTS21429X.svg
Common Questions
- What is the use of Leaxe 3.35 gm/5 ml Solution?
- At what frequency do I need to use Leaxe 3.35 gm/5 ml Solution?
- How long does it take for Leaxe 3.35 gm/5 ml Solution to work?
- What is Leaxe 3.35 gm/5 ml Solution used for?
- Is Leaxe 3.35 gm/5 ml Solution a laxative?
- What are the side effects of taking Leaxe 3.35 gm/5 ml Solution?
- Is it okay to take Leaxe 3.35 gm/5 ml Solution every day?
- Who should not be given Leaxe 3.35 gm/5 ml Solution?
- What if I take more than the recommended dose of Leaxe 3.35 gm/5 ml Solution?
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