Propa 15 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Propantheline bromide |
| Company | Labaid pharma ltd |
Indications
- Adjunctive therapy in the treatment of peptic ulcer (gastric and duodenal)
- Relief of the symptoms of gastritis
- Symptomatic treatment of diarrhoea related irritable bowel syndrome
- Urinary incontinence
- Control of salivation and enuresis
- Improves lactose intolerance
- Prevents excessive sweating (Hyperhidrosis)
Pharmacology
- Specific anticholinergic effect at the acetylcholine-receptor sites
- Direct effect upon smooth muscle
- Reduction of gastric acid secretion
- Inhibition of gastrointestinal motility
Dosage & Administration
- Usual initial adult dose of 75 mg daily
- One tablet 30 min before each meal (15 mg three times daily)
- Two tablets at bedtime
- Dosage adjustment according to individual response and tolerance
- Maximum daily dosage of 120 mg
Interaction
- Reduction of absorption by antacids or absorbent antidiarrhoeals
- Delay of absorption by anticholinergics
- Significant drug interaction with digoxin, haloperidol, corticosteroids, ketoconazole, levodopa, opioid analgesics, phenothiazines, urinary alkalizers
Contraindications
- Hypersensitivity to Propantheline bromide or other anticholinergic agents
- Glaucoma
- Obstructive disease of the gastrointestinal tract
- Obstructive uropathy
- Intestinal atony of the elderly
- Myasthenia gravis
Side Effects
- Dry mouth
- Dry skin
- Mydriasis
- Urinary retention
- Nausea
- Vomiting
- Constipation
- Headache
- Nervousness
- Mental confusion
Pregnancy & Lactation
- Pregnancy category C
- Caution in nursing women due to potential excretion in milk
Precautions & Warnings
- Use with caution in the elderly
- Use with caution in patients with autonomic neuropathy, hepatic or renal disease, hyperthyroidism, coronary heart disease, congestive heart failure, cardiac tachyarrhythmias, hypertension
Overdose Effects
- Intensification of usual side effects
- CNS disturbances
- Circulatory changes
- Respiratory failure
- Paralysis
Therapeutic Class
Anticholinergics/Anti-spasmodics
Storage Conditions
Do not store above 30°C. Keep away from light and out of the reach of children