Tiapine XR 200 mg (Tablet (Extended Release))

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00

Medicine Details

Indications

  • Treatment of Acute and chronic psychoses
  • Schizophrenia treatment
  • Bipolar disorder treatment
  • Maintenance treatment of bipolar I disorder
  • Prevention of recurrence of manic, depressive, or mixed episodes

Pharmacology

  • Atypical psychotropic agent
  • Antagonist at neurotransmitter receptors
  • Unknown mechanism of action
  • Efficacy mediated through dopamine D2 and serotonin 5HT2 antagonism

Dosage & Administration

  • Twice daily administration
  • Dosage titration for different conditions
  • Use with or without food
  • Usual effective dose range
  • Combination therapy with a mood stabilizer

Interaction

  • Caution with medicines causing electrolyte imbalance
  • Caution with medicines increasing QT interval
  • Increased clearance with certain co-administered medicines

Contraindications

  • Contra-indicated in patients hypersensitive to it

Side Effects

  • Somnolence
  • Dizziness
  • Dry mouth
  • Withdrawal symptoms
  • Elevations in serum triglyceride and total cholesterol levels
  • Weight gain
  • Decreased haemoglobin
  • Extrapyramidal symptoms

Pregnancy & Lactation

  • Safety and efficacy not established during human pregnancy
  • Use only if benefits justify potential risks
  • Avoid breastfeeding while taking the medicine

Precautions & Warnings

  • Increased risk of suicidal thoughts
  • Caution in patients with cardiovascular disease
  • Caution in patients with a history of seizures
  • Consideration of dose reduction or discontinuation for tardive dyskinesia
  • Neuroleptic Malignant Syndrome caution
  • Caution in patients with cardiovascular disease or family history of QT prolongation
  • Reports of severe neutropenia
  • Observation of blood glucose and hyperglycemia

Use in Special Populations

  • Caution in the elderly
  • Lower dose and slower titration in the elderly
  • Not indicated for use in children and adolescents below 18 years of age

Overdose Effects

  • Survival reported in acute overdoses up to 30 grams
  • No specific antidote
  • Consideration of multiple drug involvement
  • Intensive care procedures recommended
  • Close medical supervision and monitoring

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Keep out of the sight and reach of children
  • Do not use after expiry date
  • Store in a cool and dry place away from light

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