Qutipin SR 300 mg (Tablet (Sustained Release))
Unit Price: ৳ 22.00 (3 x 10: ৳ 660.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Sun pharmaceutical bangladesh ltd |
| Also available as |
Indications
- Treatment of acute and chronic psychoses
- Treatment of schizophrenia
- Treatment of bipolar disorder
- Maintenance treatment of bipolar I disorder
- Prevention of recurrence of manic, depressive or mixed episodes
Pharmacology
- Belongs to dibenzothiazepine derivatives
- Antagonist at multiple neurotransmitter receptors
- No appreciable affinity at cholinergic muscarinic and benzodiazepine receptors
- Mechanism of action is unknown
- Efficacy in schizophrenia is mediated through dopamine D2 and serotonin 5HT2 antagonism
Dosage & Administration
- Administered twice daily
- Total daily dose for the first four days
- Usual effective dose range
- First four days dosage for manic episodes
- Dosage adjustments for depressive episodes
- Combination therapy with a mood stabilizer
Interaction
- Caution with medicines known to cause electrolyte imbalance
- Potential interactions with thioridazine, carbamazepine, phenytoin
Contraindications
- Contra-indicated in patients who are hypersensitive to it
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Withdrawal symptoms
- Elevations in serum triglyceride levels
- Weight gain
- Extrapyramidal symptoms
Pregnancy & Lactation
- Safety and efficacy during human pregnancy not established
- Use during pregnancy only if benefits justify potential risks
- Excretion into human milk is unknown
Precautions & Warnings
- Increased risk of suicidal thoughts and self-harm
- Caution in patients with cardiovascular disease
- Caution in patients with a history of seizures
- Consideration for tardive dyskinesia and EPS
- Caution in patients with a family history of QT prolongation
- Potential occurrence of severe neutropenia
- Observation of increases in blood glucose and hyperglycemia
Use in Special Populations
- Caution in the elderly
- Not indicated for use in children and adolescents below 18 years of age
Overdose Effects
- Survival reported in acute overdoses
- No specific antidote
- Consideration of multiple drug involvement
- Recommendation for intensive care procedures
- Treatment options for refractory hypotension
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of the sight and reach of children
- Do not use after the expiry date
- Store in a cool and dry place away from light